[HTML][HTML] Lessons from the post-genomic era: Globin diversity beyond oxygen binding and transport

A Keppner, D Maric, M Correia, TW Koay, IMC Orlando… - Redox biology, 2020 - Elsevier
Vertebrate hemoglobin (Hb) and myoglobin (Mb) were among the first proteins whose
structures and sequences were determined over 50 years ago. In the subsequent …

Emerging role of the nucleolar stress response in autophagy

AS Pfister - Frontiers in cellular neuroscience, 2019 - frontiersin.org
Autophagy represents a conserved self-digestion program, which allows regulated
degradation of cellular material. Autophagy is activated by cellular stress, serum starvation …

Transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampus

L Que, D Lukacsovich, W Luo, C Földy - Nature Communications, 2021 - nature.com
The diversity reflected by> 100 different neural cell types fundamentally contributes to brain
function and a central idea is that neuronal identity can be inferred from genetic information …

[HTML][HTML] Detection of SARS-CoV-2 genome and whole transcriptome sequencing in frontal cortex of COVID-19 patients

S Gagliardi, ET Poloni, C Pandini, M Garofalo… - Brain, Behavior, and …, 2021 - Elsevier
SARS-Cov-2 infection is frequently associated with Nervous System manifestations.
However, it is not clear how SARS-CoV-2 can cause neurological dysfunctions and which …

Mast cells in neurodegenerative disease

MK Jones, A Nair, M Gupta - Frontiers in cellular neuroscience, 2019 - frontiersin.org
Neurodegenerative diseases affect millions of people worldwide, yet there are currently no
effective treatments. Because risk of neurodegenerative disease substantially increases with …

Xanthine-induced deficits in hippocampal behavior and abnormal expression of hemoglobin genes

J Kambe, S Miyata, C Li, Y Yamamoto… - Behavioural Brain …, 2023 - Elsevier
The prevalence of mental disorders such as depression and anxiety is high and often
comorbid with other diseases. Chronic stress is a common risk factor for these disorders, but …

Physiological and pathological functions of neuronal hemoglobin: a key underappreciated protein in Parkinson's disease

R Zheng, Y Yan, J Pu, B Zhang - International Journal of Molecular …, 2022 - mdpi.com
The expression of Hemoglobin (Hb) is not restricted to erythrocytes but is also present in
neurons. Hb is selectively enriched in vulnerable mesencephalic dopaminergic neurons of …

Unraveling the Interplay of Dopamine, Carbon Monoxide, and Heme Oxygenase in Neuromodulation and Cognition

N Bauer, D Liu, TP Nguyen, B Wang - ACS Chemical …, 2024 - ACS Publications
The dopaminergic system plays important roles in neuromodulation, including prominent
roles in complex neurological functions such as cognition, reward, motivation, and memory …

Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS

S Waters, MEV Swanson, BV Dieriks, YB Zhang… - Acta neuropathologica …, 2021 - Springer
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving
progressive degeneration of upper and lower motor neurons. The pattern of lower motor …

Involvement of hemoglobins in the pathophysiology of Alzheimer's disease

MA Altinoz, S Guloksuz, R Schmidt-Kastner… - Experimental …, 2019 - Elsevier
Hemoglobins (Hbs) are heme-containing proteins binding oxygen, carbon monoxide, and
nitric oxide. While erythrocytes are the most well-known location of Hbs, Hbs also exist in …