Triazoles, nitrogen-containing heterocycles, have gained attention for their applications in
medicinal chemistry, drug discovery, agrochemicals, and material sciences. In the current …

In this work, the synthesis, characterization, and biological activities of a new series of 1, 3, 4‐
thiadiazole derivatives were investigated. The structures of final compounds were identified …

Invasive fungal infections cause serious illness and death worldwide. Long-term therapeutic
and preventative use of antifungal drugs in high-risk patients has caused resistance …

Chagas disease, a silent but widespread disease that mainly affects a socioeconomically
vulnerable population, lacks innovative safe drug therapy. The available drugs …

Discovery of new antifungal agents is of great importance due to the increased prevalence
of fungal infections and the emergence of drug-resistant strains. 1, 2, 4-Triazole derivatives …

In this study, the potential of using 3, 5-bis (5-mercapto-4-R-4H-1, 2, 4-triazol-3-yl) phenol as
a critical component for the synthesis of new compounds is considered, which may be of …

Abstract Derivatives of 5, 7-diacyl-3-H (alkyl)-6-aryl-5H-[1, 2, 4] triazolo [3, 4-b][1, 3, 4]
thiadiazine. Aim. To evaluate the dose dependence of the analgesic effect of the compound …

First, we synthesized various compounds four, five and seven-membered heterocyclic
derives from Schiff bases with the goal of conducting an organic synthesis and biological …

Анотація Вступ. Значна поширеність холодових уражень, недостатня ефективність
запобігання та лікування гострої холодової травми зумовлюють актуальність пошуку …