Living organisms such as bacteria are often exposed to continuous changes in the nutrient
availability in nature. Therefore, bacteria must constantly monitor the environmental …

Highlights•Heterogeneity in phenotype and growth rate of single cells affect stress
survival.•Single-cell stress responses in biofilms and interspecies interactions can alter …

Cell-to-cell heterogeneity in gene expression and growth can have critical functional
consequences, such as determining whether individual bacteria survive or die following …

The inherent stochasticity of metabolism raises a critical question for understanding
homeostasis: are cellular processes regulated in response to internal fluctuations? Here, we …

The widespread occurrence of sulfonamides raises significant concerns about the evolution
and spread of antibiotic resistance genes. Biodegradation represents not only a resistance …

In microbiology, accessing single-cell information within large populations is pivotal. Here
we introduce bio-sCAPA, a technique for patterning bacterial cells in defined geometric …

Abstract The Pareto principle, or 20: 80 rule, describes resource distribution in stable
communities whereby 20% of community members acquire 80% of a key resource. In this …

In fluctuating environments, many microorganisms acquire phenotypic heterogeneity as a
survival tactic to increase the likelihood of survival of the overall population. One example of …

Streptococcus pneumoniae is an important human pathogen, being one of the most
common causes of community-acquired pneumonia and otitis media. Antibiotic resistance in …

Biotechnology is widely used in bioproduction to transform waste into valuable products. A
comprehensive understanding of the kinetics involved is crucial for optimizing system …