Women with multifocal or multicentric breast tumors (multifocality henceforth) have been
reported to have greater probability of nodal metastasis and relapse and worse survival than …

An understanding of prognostic factors in breast cancer is imperative for guiding patient
care. Increased tumor size and more advanced nodal status are established independent …

Sažetak A young woman with breast cancer is considered to be a woman younger than 40.
According to the literature, breast cancer in the population of young women usually is of a …

More than 750 000 women in Italy are surviving a diagnosis of breast cancer. A large body
of literature tells us which characteristics impact the most on their prognosis. However, the …

Background The biological and clinical significance of multifocal and multicentric (MF/MC)
breast cancers and the choice of appropriate surgical treatment for these tumors are still …

Background The impact of tumor focality on type of surgery, local recurrence rate, and
survival after neoadjuvant chemotherapy (NACT) for breast cancer is not fully understood …

Background The clinicopathological characteristics and the prognostic significance of
multifocal (MF) and multicentric (MC) breast cancers are not well established. Patients and …

Background The prognostic equivalence between mastectomy and breast-conserving
surgery (BCS) followed by radiotherapy was shown in pivotal trials conducted decades ago …

Purpose To assess whether breast cancer molecular subtype classified by surrogate
markers can be used to predict the extent of clinically relevant disease with preoperative …

The prognostic information implied in subgross morphologic parameters such as lesion
distribution (unifocal, multifocal, or diffuse) and disease extent in breast cancer has …