Molecular mechanisms of mitochondrial dynamics
Mitochondria not only synthesize energy required for cellular functions but are also involved
in numerous cellular pathways including apoptosis, calcium homoeostasis, inflammation …
in numerous cellular pathways including apoptosis, calcium homoeostasis, inflammation …
Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance
Coronary microvascular endothelial dysfunction is both a culprit and a victim of diabetes,
and can accelerate diabetes-related microvascular and macrovascular complications by …
and can accelerate diabetes-related microvascular and macrovascular complications by …
[HTML][HTML] Mitochondrial alterations in fatty liver diseases
B Fromenty, M Roden - Journal of hepatology, 2023 - Elsevier
Fatty liver diseases can result from common metabolic diseases, as well as from xenobiotic
exposure and excessive alcohol use, all of which have been shown to exert toxic effects on …
exposure and excessive alcohol use, all of which have been shown to exert toxic effects on …
Nrf2 as a regulator of mitochondrial function: Energy metabolism and beyond
N Esteras, AY Abramov - Free Radical Biology and Medicine, 2022 - Elsevier
Mitochondria are unique and essential organelles that mediate many vital cellular processes
including energy metabolism and cell death. The transcription factor Nrf2 (NF-E2 p45 …
including energy metabolism and cell death. The transcription factor Nrf2 (NF-E2 p45 …
TMBIM6 prevents VDAC1 multimerization and improves mitochondrial quality control to reduce sepsis-related myocardial injury
Background The regulatory mechanisms involved in mitochondrial quality control (MQC)
dysfunction during septic cardiomyopathy (SCM) remain incompletely characterized …
dysfunction during septic cardiomyopathy (SCM) remain incompletely characterized …
Mitochondrial dysfunctions induce PANoptosis and ferroptosis in cerebral ischemia/reperfusion injury: from pathology to therapeutic potential
R She, D Liu, J Liao, G Wang, J Ge… - Frontiers in Cellular …, 2023 - frontiersin.org
Ischemic stroke (IS) accounts for more than 80% of the total stroke, which represents the
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …
The Drp1-mediated mitochondrial fission protein interactome as an emerging core player in mitochondrial dynamics and cardiovascular disease therapy
Mitochondria, the membrane-bound cell organelles that supply most of the energy needed
for cell function, are highly regulated, dynamic organelles bearing the ability to alter both …
for cell function, are highly regulated, dynamic organelles bearing the ability to alter both …
BNIP3L/NIX-mediated mitophagy: molecular mechanisms and implications for human disease
Y Li, W Zheng, Y Lu, Y Zheng, L Pan, X Wu… - Cell Death & …, 2021 - nature.com
Mitophagy is a highly conserved cellular process that maintains the mitochondrial quantity
by eliminating dysfunctional or superfluous mitochondria through autophagy machinery. The …
by eliminating dysfunctional or superfluous mitochondria through autophagy machinery. The …
Targeting mitochondria in cancer therapy: Insight into photodynamic and photothermal therapies
Mitochondria are critical multifunctional organelles in cells that generate power, produce
reactive oxygen species, and regulate cell survival. Mitochondria that are dysfunctional are …
reactive oxygen species, and regulate cell survival. Mitochondria that are dysfunctional are …
Lipid nanodiscs for high-resolution NMR studies of membrane proteins
Membrane proteins (MPs) play essential roles in numerous cellular processes. Because
around 70% of the currently marketed drugs target MPs, a detailed understanding of their …
around 70% of the currently marketed drugs target MPs, a detailed understanding of their …