Perioperative use of gabapentinoids for the management of postoperative acute pain: a systematic review and meta-analysis

M Verret, F Lauzier, R Zarychanski, C Perron… - …, 2020 - ingentaconnect.com
Background: Widely used for acute pain management, the clinical benefit from perioperative
use of gabapentinoids is uncertain. The aim of this systematic review was to assess the …

Inappropriate opioid prescription after surgery

MD Neuman, BT Bateman, H Wunsch - The Lancet, 2019 - thelancet.com
Worldwide, the use of prescription opioid analgesics more than doubled between 2001 and
2013, with several countries, including the USA, Canada, and Australia, experiencing …

Multimodal analgesia

A O'Neill, P Lirk - Anesthesiology clinics, 2022 - anesthesiology.theclinics.com
Inadequate perioperative pain is, unfortunately, frequent, and has clinically relevant
consequences, including decreased patient satisfaction, delayed postoperative mobilization …

Pharmacotherapy for the prevention of chronic pain after surgery in adults: an updated systematic review and meta-analysis

ME Carley, LE Chaparro, M Choinière, H Kehlet… - …, 2021 - ingentaconnect.com
Background: Chronic postsurgical pain can severely impair patient health and quality of life.
This systematic review update evaluated the effectiveness of systemic drugs to prevent …

Postoperative pain management in the era of ERAS: an overview

GP Joshi, H Kehlet - Best Practice & Research Clinical Anaesthesiology, 2019 - Elsevier
Enhanced recovery after surgery (ERAS) programmes are increasingly becoming standard
of care for several surgical procedures. However, compliance with ERAS protocols including …

Enhanced recovery and surgical optimization protocol for minimally invasive gynecologic surgery: an AAGL white paper

R Stone, E Carey, AN Fader, J Fitzgerald… - Journal of minimally …, 2021 - Elsevier
This is the first Enhanced Recovery After Surgery (ERAS) guideline dedicated to
standardizing and optimizing perioperative care for women undergoing minimally invasive …

Association of gabapentinoids with the risk of opioid-related adverse events in surgical patients in the United States

K Bykov, BT Bateman, JM Franklin, SM Vine… - JAMA network …, 2020 - jamanetwork.com
Importance The use of gabapentinoids in multimodal postoperative analgesia is increasing;
however, when coadministered with opioids, these drugs may potentiate central nervous …

Perioperative gabapentin use and in-hospital adverse clinical events among older adults after major surgery

CM Park, SK Inouye, ER Marcantonio… - JAMA Internal …, 2022 - jamanetwork.com
Importance Gabapentin has been increasingly used as part of a multimodal analgesia
regimen to reduce opioid use in perioperative pain management. However, the safety of …

Gabapentinoids: pharmacokinetics, pharmacodynamics and considerations for clinical practice

M Chincholkar - British journal of pain, 2020 - journals.sagepub.com
The gabapentinoids are often recommended as first-line treatments for the management of
neuropathic pain. The differing pharmacodynamic and pharmacokinetic profiles can have …

Pharmacologic therapy for acute pain

O Amaechi, MMC Human, K Featherstone - American family physician, 2021 - aafp.org
Pharmacologic management of acute pain should be tailored for each patient, including a
review of treatment expectations and a plan for the time course of prescriptions …