Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Abstract Ectodomain phosphatase/phosphodiesterase-1 (ENPP1) is overexpressed on
cancer cells and functions as an innate immune checkpoint by hydrolyzing extracellular …

It is now well accepted that plasma cells can become long-lived (memory) plasma cells and
secrete antibodies for months, years or a lifetime. However, the mechanisms involved in this …

Durable humoral immunity is dependent upon the generation of antigen-specific antibody
titers, produced by non-proliferating bone marrow resident long-lived plasma cells (LLPC) …

Many aspects of SARS-CoV-2 have fully conformed with the principles established by
decades of viral immunology research, ultimately leading to the crowning achievement of …

The transcription factor, forkhead box M1 (FOXM1), has been implicated in the natural
history and outcome of newly diagnosed high-risk myeloma (HRMM) and relapsed/refractory …

Antibody secreting cells (ASCs) are terminally differentiated cells of the humoral immune
response and must adapt morphologically, transcriptionally, and metabolically to maintain …

Antibody‐secreting cells (ASC) are the effectors of protective humoral immunity and the only
cell type that produces antibodies or immunoglobulins in mammals. In addition to their …

Plasma cells (PC) are key to protective immunity because they secrete antibodies. Surviving
for periods ranging from days to decades in mammals, PC possess varying survival times …