Innovative therapeutic approaches in non-alcoholic fatty liver disease: When knowing your patient is key
M Alonso-Peña, M Del Barrio, A Peleteiro-Vigil… - International Journal of …, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of disorders ranging
from simple steatosis to non-alcoholic steatohepatitis (NASH). Hepatic steatosis may result …
from simple steatosis to non-alcoholic steatohepatitis (NASH). Hepatic steatosis may result …
Nicotinic acid attenuates experimental non-alcoholic steatohepatitis by inhibiting the NLRP3 inflammasome/pyroptosis pathway
I Cardoso-Lezama, MÁ Fuentes-Figueroa… - Biochemical …, 2023 - Elsevier
Non-alcoholic steatohepatitis (NASH) is a global public health concern that may progress
into fibrosis, cirrhosis, and liver cancer, with limited curative treatment options. While the …
into fibrosis, cirrhosis, and liver cancer, with limited curative treatment options. While the …
[HTML][HTML] Role of pattern recognition receptors in the development of MASLD and potential therapeutic applications
L Yu, F Gao, Y Li, D Su, L Han, Y Li, X Zhang… - Biomedicine & …, 2024 - Elsevier
Metabolic dysfunction-associated steatotic liver disease (MASLD) has become one of the
most prevalent liver diseases worldwide, and its occurrence is strongly associated with …
most prevalent liver diseases worldwide, and its occurrence is strongly associated with …
Integrating single-cell and bulk sequencing data to identify glycosylation-based genes in non-alcoholic fatty liver disease-associated hepatocellular carcinoma
Z Zhou, Y Gao, L Deng, X Lu, Y Lai, J Wu, S Chen, C Li… - PeerJ, 2024 - peerj.com
Background The incidence of non-alcoholic fatty liver disease (NAFLD) associated
hepatocellular carcinoma (HCC) has been increasing. However, the role of glycosylation, an …
hepatocellular carcinoma (HCC) has been increasing. However, the role of glycosylation, an …
Self‐recognition through Dectin‐1 exacerbates liver inflammation
S Torigoe, DW Lowman, T Sugiki, DL Williams… - Genes to …, 2024 - Wiley Online Library
Dectin‐1 is a well‐characterized C‐type lectin receptor involved in anti‐fungal immunity
through the recognition of polysaccharides; however, molecular mechanisms and outcomes …
through the recognition of polysaccharides; however, molecular mechanisms and outcomes …
Identification and validation of immune-related gene signature models for predicting prognosis and immunotherapy response in hepatocellular carcinoma
Z Liu, L Yang, C Liu, Z Wang, W Xu, J Lu… - Frontiers in …, 2024 - frontiersin.org
Background This study seeks to enhance the accuracy and efficiency of clinical diagnosis
and therapeutic decision-making in hepatocellular carcinoma (HCC), as well as to optimize …
and therapeutic decision-making in hepatocellular carcinoma (HCC), as well as to optimize …
Innate Immunity and CKD: Is There a Significant Association?
M Plonsky-Toder, D Magen, S Pollack - Cells, 2023 - mdpi.com
Chronic kidney disease (CKD) constitutes a worldwide epidemic, affecting approximately
10% of the global population, and imposes significant medical, psychological, and financial …
10% of the global population, and imposes significant medical, psychological, and financial …
Available and novel plant-based carbon dots derived from Vaccaria Semen carbonisata alleviates liver fibrosis
Y Zhao, E Dai, L Dong, J Yuan, Y Zhao, T Wu… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Liver fibrosis represents an intermediate stage in the progression of liver
disease, and as of now, there exists no established clinical therapy for effective antifibrotic …
disease, and as of now, there exists no established clinical therapy for effective antifibrotic …
Role of serum endotoxin, FGF19, TLR2, TNF-α, IL-12 and IL-10 in NAFLD-associated T2DM pathogenesis: Insights into Th1 bias and protective mechanisms
SJ Das, B Pathak, S Dutta, S Bose, PD Bose - Indian Journal of …, 2024 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) in non-obese patients is
pathophysiologically distinct, exhibiting common immunological link with type-2 diabetes …
pathophysiologically distinct, exhibiting common immunological link with type-2 diabetes …
Cost-effectiveness analysis of HCC surveillance in nonalcoholic fatty liver disease cirrhosis using US visualization score C-triggered abbreviated MRI
A Mulgaonkar, DQ Huang, H Siddiqi… - Official journal of the …, 2022 - journals.lww.com
Objectives: Ultrasound (US) is associated with severe visualization limitations (LI-RADS
Visualization score C) in one-third of patients with nonalcoholic fatty liver disease (NAFLD) …
Visualization score C) in one-third of patients with nonalcoholic fatty liver disease (NAFLD) …