Mammographic density phenotypes and risk of breast cancer: a meta-analysis

A Pettersson, RE Graff, G Ursin… - Journal of the …, 2014 - academic.oup.com
Background Fibroglandular breast tissue appears dense on mammogram, whereas fat
appears nondense. It is unclear whether absolute or percentage dense area more strongly …

Mammographic density—a review on the current understanding of its association with breast cancer

CW Huo, GL Chew, KL Britt, WV Ingman… - Breast cancer research …, 2014 - Springer
There has been considerable recent interest in the genetic, biological and epidemiological
basis of mammographic density (MD), and the search for causative links between MD and …

Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25

L Fejerman, N Ahmadiyeh, D Hu, S Huntsman… - Nature …, 2014 - nature.com
The genetic contributions to breast cancer development among Latinas are not well
understood. Here we carry out a genome-wide association study of breast cancer in Latinas …

Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk

S Lindström, DJ Thompson, AD Paterson, J Li… - Nature …, 2014 - nature.com
Mammographic density reflects the amount of stromal and epithelial tissues in relation to
adipose tissue in the breast and is a strong risk factor for breast cancer. Here we report the …

Evidence of gene–environment interactions between common breast cancer susceptibility loci and established environmental risk factors

S Nickels, T Truong, R Hein, K Stevens, K Buck… - PLoS …, 2013 - journals.plos.org
Various common genetic susceptibility loci have been identified for breast cancer; however,
it is unclear how they combine with lifestyle/environmental risk factors to influence risk. We …

Preliminary evaluation of the publicly available Laboratory for Breast Radiodensity Assessment (LIBRA) software tool: comparison of fully automated area and …

BM Keller, J Chen, D Daye, EF Conant, D Kontos - Breast cancer research, 2015 - Springer
Introduction Breast density, commonly quantified as the percentage of mammographically
dense tissue area, is a strong breast cancer risk factor. We investigated associations …

Biomarkers in patients with metastatic breast cancer and the PRAEGNANT study network

PA Fasching, SY Brucker, TN Fehm… - Geburtshilfe und …, 2015 - thieme-connect.com
Progress has been made in the treatment of metastatic breast cancer in recent decades, but
very few therapies use patient or tumor-specific characteristics to tailor individualized …

Racial differences in quantitative measures of area and volumetric breast density

AM McCarthy, BM Keller, LM Pantalone… - Journal of the …, 2016 - academic.oup.com
Background: Increased breast density is a strong risk factor for breast cancer and also
decreases the sensitivity of mammographic screening. The purpose of our study was to …

Raised mammographic density: causative mechanisms and biological consequences

MJ Sherratt, JC McConnell, CH Streuli - Breast Cancer Research, 2016 - Springer
High mammographic density is the most important risk factor for breast cancer, after ageing.
However, the composition, architecture, and mechanical properties of high X-ray density soft …

Diagnostic accuracy and recall rates for digital mammography and digital mammography combined with one-view and two-view tomosynthesis: results of an enriched …

EA Rafferty, JM Park, LE Philpotts… - American Journal of …, 2014 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to compare two methods of combining
tomosynthesis with digital mammography by assessing diagnostic accuracy and recall rates …