On the expansion of biological functions of lytic polysaccharide monooxygenases

TM Vandhana, JL Reyre, D Sushmaa… - New …, 2022 - Wiley Online Library
Lytic polysaccharide monooxygenases (LPMOs) constitute an enigmatic class of enzymes,
the discovery of which has opened up a new arena of riveting research. LPMOs can …

Oxidoreductases and reactive oxygen species in conversion of lignocellulosic biomass

B Bissaro, A Várnai, ÅK Røhr… - … and Molecular Biology …, 2018 - Am Soc Microbiol
Biomass constitutes an appealing alternative to fossil resources for the production of
materials and energy. The abundance and attractiveness of vegetal biomass come along …

Lytic polysaccharide monooxygenases in enzymatic processing of lignocellulosic biomass

P Chylenski, B Bissaro, M Sørlie, ÅK Røhr, A Várnai… - Acs …, 2019 - ACS Publications
The discovery of lytic polysaccharide monooxygenases (LPMOs) has revolutionized
enzymatic processing of polysaccharides, in particular, recalcitrant insoluble …

Lytic polysaccharide monooxygenases: enzymes for controlled and site-specific Fenton-like chemistry

B Bissaro, VGH Eijsink - Essays in biochemistry, 2023 - portlandpress.com
The discovery of oxidative cleavage of glycosidic bonds by enzymes currently known as lytic
polysaccharide monooxygenases (LPMOs) has profoundly changed our current …

Experimental models to study intestinal microbes–mucus interactions in health and disease

L Etienne-Mesmin, B Chassaing… - FEMS microbiology …, 2019 - academic.oup.com
ABSTRACT A close symbiotic relationship exists between the intestinal microbiota and its
host. A critical component of gut homeostasis is the presence of a mucus layer covering the …

Biofilm matrix proteins

JNC Fong, FH Yildiz - Microbial biofilms, 2015 - Wiley Online Library
Microorganisms in the natural environment typically live on or in close association with
surfaces and predominantly exist as biofilms, surface attached microbial communities …

Structural diversity of lytic polysaccharide monooxygenases

G Vaaje-Kolstad, Z Forsberg, JSM Loose… - Current opinion in …, 2017 - Elsevier
Highlights•LPMOs show large structural and sequence variability that affect substrate-
interaction surfaces.•First X-ray crystallographic data on cellulose binding.•Large modular …

Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia

F Askarian, CM Tsai, G Cordara… - Proceedings of the …, 2023 - National Acad Sciences
Pseudomonas aeruginosa (PA) CbpD belongs to the lytic polysaccharide monooxygenases
(LPMOs), a family of enzymes that cleave chitin or related polysaccharides. Here, we …

Oxygen activation by Cu LPMOs in recalcitrant carbohydrate polysaccharide conversion to monomer sugars

KK Meier, SM Jones, T Kaper, H Hansson… - Chemical …, 2017 - ACS Publications
Natural carbohydrate polymers such as starch, cellulose, and chitin provide renewable
alternatives to fossil fuels as a source for fuels and materials. As such, there is considerable …

The chitinolytic machinery of Serratia marcescens – a model system for enzymatic degradation of recalcitrant polysaccharides

G Vaaje‐Kolstad, SJ Horn, M Sørlie… - The FEBS …, 2013 - Wiley Online Library
The chitinolytic machinery of S erratia marcescens is one of the best known enzyme systems
for the conversion of insoluble polysaccharides. This machinery includes four chitin‐active …