Phytosynthesized metal oxide nanoparticles for pharmaceutical applications

S Andra, SK Balu, J Jeevanandham… - Naunyn-Schmiedeberg's …, 2019 - Springer
Developments in nanotechnology field, specifically, metal oxide nanoparticles have
attracted the attention of researchers due to their unique sensing, electronic, drug delivery …

Metallic nanoantioxidants as potential therapeutics for type 2 diabetes: a hypothetical background and translational perspectives

O Lushchak, A Zayachkivska… - Oxidative medicine and …, 2018 - Wiley Online Library
Hyperglycemia‐induced overproduction of reactive oxygen species (ROS) is an important
contributor to type 2 diabetes (T2D) pathogenesis. The conventional antioxidant therapy …

Dietary exposure of copper and zinc oxides nanoparticles affect the fitness, enzyme activity, and microbial community of the model insect, silkworm Bombyx mori

A Muhammad, J He, T Yu, C Sun, D Shi, Y Jiang… - Science of the Total …, 2022 - Elsevier
Copper and Zinc oxides nanoparticles (CuO and ZnO NPs, respectively) are among the
most produced and commonly used engineered nanomaterials. They can be released into …

Drosophila as a Suitable In Vivo Model in the Safety Assessment of Nanomaterials

E Demir, FT Demir, R Marcos - Nanotoxicology in Safety Assessment of …, 2022 - Springer
Nanotechnology is often praised as the future technology that will revolutionize the world as
we know it, because nanomaterials (NMs) offer numerous practical applications for a wide …

Recent Advances in KEAP1/NRF2-Targeting Strategies by Phytochemical Antioxidants, Nanoparticles, and Biocompatible Scaffolds for the Treatment of Diabetic …

A Rampin, M Carrabba, M Mutoli, CL Eman… - Antioxidants & Redox …, 2022 - liebertpub.com
Significance: Modulation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-mediated
antioxidant response is a key aspect in the onset of diabetes-related cardiovascular …

Polyvinylpyrrolidone-Capped Copper Oxide Nanoparticles-Anchored Pramipexole Attenuates the Rotenone-Induced Phenotypes in a Drosophila Parkinson's …

R Hanumanthappa, DM Venugopal, N PC, A Shaikh… - ACS …, 2023 - ACS Publications
Parkinson's disease (PD) is a progressive, age-related neurodegenerative disease. The
disease is characterized by the loss of dopaminergic neurons in the substantia nigra, pars …

Biochemical CuSO4 Toxicity in Drosophila melanogaster Depends on Sex and Developmental Stage of Exposure

PT Halmenschelager, JBT da Rocha - Biological trace element research, 2019 - Springer
Copper is a transition metal that exists in different chemical forms (eg, Cu 2+, Cu+, and Cu 0)
and at high concentrations it is toxic. Here, we investigated the Cu 2+-induced toxicity in …

Hazard assessment of the effects of acute and chronic exposure to permethrin, copper hydroxide, acephate, and validamycin nanopesticides on the physiology of …

E Demir, S Kansız, M Doğan, Ö Topel… - International Journal of …, 2022 - mdpi.com
New insights into the interactions between nanopesticides and edible plants are required in
order to elucidate their impacts on human health and agriculture. Nanopesticides include …

Ameliorative effects of melatonin against nano and ionic cobalt induced genotoxicity in two in vivo Drosophila assays

H Ertuğrul, B Yalçın, M Güneş… - Drug and Chemical …, 2020 - Taylor & Francis
The aim of this study is to evaluate the ameliorative effect of melatonin (MEL) against
induced genotoxicity by cobalt (II) chloride (CoCl2) and cobalt nanoparticles (CoNPs)(50 …

Genotoxicity and cellular uptake of nanosized and fine copper oxide particles in human bronchial epithelial cells in vitro

KM Siivola, S Suhonen, M Hartikainen… - … /Genetic Toxicology and …, 2020 - Elsevier
We studied the genotoxicity and cellular uptake of nanosized (< 50 nm) and fine (< 10 μm)
copper oxide (CuO) particles in vitro in human bronchial epithelial (BEAS-2B) cells. In …