[HTML][HTML] Telomere biology and age-related diseases

M Herrmann, I Pusceddu, W März… - Clinical Chemistry and …, 2018 - degruyter.com
Telomeres are the protective end caps of chromosomes and shorten with every cell division.
Telomere length has been proposed as a biomarker of biological age and a risk factor for …

Vitamin D status in patients with systemic lupus erythematosus (SLE): A systematic review and meta-analysis

MA Islam, SS Khandker, SS Alam, P Kotyla… - Autoimmunity …, 2019 - Elsevier
Background Systemic lupus erythematosus (SLE) is a systemic autoimmune disease where
chronic inflammation and tissue or organ damage is observed. Due to various suspected …

Vitamin D deficiency accelerates ageing and age‐related diseases: a novel hypothesis

MJ Berridge - The Journal of physiology, 2017 - Wiley Online Library
Ageing can occur at different rates, but what controls this variable rate is unknown. Here I
have developed a hypothesis that vitamin D may act to control the rate of ageing. The basis …

[HTML][HTML] The telomere/telomerase system in chronic inflammatory diseases. Cause or effect?

V Kordinas, A Ioannidis, S Chatzipanagiotou - Genes, 2016 - mdpi.com
Telomeres are specialized nucleoprotein structures located at the end of linear
chromosomes and telomerase is the enzyme responsible for telomere elongation …

Vitamin D supplementation improves cognitive function through reducing oxidative stress regulated by telomere length in older adults with mild cognitive impairment: a …

T Yang, H Wang, Y Xiong, C Chen… - Journal of …, 2020 - content.iospress.com
Background: Cognitive decline in older adults is a serious public health problem today.
Association between vitamin D supplementation and cognition remains controversial …

Vitamin D, steroid hormones, and autoimmunity

M Cutolo, S Paolino, A Sulli, V Smith… - Annals of the New …, 2014 - Wiley Online Library
The endogenous serum metabolite of vitamin D (calcitriol, 1, 25 (OH) 2D3) is considered a
true steroid hormone (D hormone), and like glucocorticoids (GCs) and gonadal hormones …

[HTML][HTML] Seasonal variation in vitamin D in association with age, inflammatory cytokines, anthropometric parameters, and lifestyle factors in older adults

L Elizondo-Montemayor, EC Castillo… - Mediators of …, 2017 - hindawi.com
Vitamin D deficiency is present even in sunny regions. Ageing decreases pre-vitamin D
production in the skin and is associated with altered cytokine profile. We performed a …

Association between circulating 25‐hydroxyvitamin D and systemic lupus erythematosus: A systematic review and meta‐analysis

SY Guan, HY Cai, P Wang, TT Lv, LN Liu… - International Journal …, 2019 - Wiley Online Library
Aim The indicators for measuring vitamin D are various, and 25‐hydroxyvitamin D (25 (OH)
D) is considered as the optimal indicator of total vitamin D levels. In this study, we aim to …

[HTML][HTML] The role of telomeres and vitamin D in cellular aging and age-related diseases

I Pusceddu, CJL Farrell, AM Di Pierro… - Clinical Chemistry and …, 2015 - degruyter.com
Aging is a complex biological process characterized by a progressive decline of organ
functions leading to an increased risk of age-associated diseases and death. Decades of …

The relationship between vitamin D and telomere/telomerase: a comprehensive review

M Zarei, M Zarezadeh, F Hamedi Kalajahi… - The Journal of Frailty & …, 2021 - Springer
Telomeres are repetitive nucleotide sequences that together with the associated sheltrin
complex protect the ends of chromosomes and maintain genomic stability. Evidences from …