[HTML][HTML] DNA methylation in lung cancer patients: Opening a" window of life" under precision medicine

R Liang, X Li, W Li, X Zhu, C Li - Biomedicine & Pharmacotherapy, 2021 - Elsevier
DNA methylation is a work of adding a methyl group to the 5th carbon atom of cytosine in
DNA sequence under the catalysis of DNA methyltransferase (DNMT) to produce 5-methyl …

Transcriptomic comparison of human and mouse brain microvessels

HW Song, KL Foreman, BD Gastfriend, JS Kuo… - Scientific reports, 2020 - nature.com
The brain vasculature maintains brain homeostasis by tightly regulating ionic, molecular,
and cellular transport between the blood and the brain parenchyma. These blood–brain …

Methylomics and cancer: the current state of methylation profiling and marker development for clinical care

C Liu, H Tang, N Hu, T Li - Cancer Cell International, 2023 - Springer
Epigenetic modifications have long been recognized as an essential level in transcriptional
regulation linking behavior and environmental conditions or stimuli with biological …

UHRF1 inhibition epigenetically reprograms cancer stem cells to suppress the tumorigenic phenotype of hepatocellular carcinoma

Y Wang, P Hu, F Wang, S Xi, S Wu, L Sun, Y Du… - Cell Death & …, 2023 - nature.com
Cancer stem cells (CSCs) contribute to tumor initiation, progression, and recurrence in many
types of cancer, including hepatocellular carcinoma (HCC). Epigenetic reprogramming of …

Histone-Related Genes Are Hypermethylated in Lung Cancer and Hypermethylated HIST1H4F Could Serve as a Pan-Cancer Biomarker

S Dong, W Li, L Wang, J Hu, Y Song, B Zhang, X Ren… - Cancer Research, 2019 - AACR
Lung cancer is the leading cause of cancer-related deaths worldwide. Cytologic
examination is the current “gold standard” for lung cancer diagnosis, however, this has low …

[HTML][HTML] The outpost against cancer: universal cancer only markers

C Qian, X Zou, W Li, Y Li, W Yu - Cancer Biology & Medicine, 2023 - ncbi.nlm.nih.gov
Cancer is the leading cause of death worldwide. Early detection of cancer can lower the
mortality of all types of cancer; however, effective early-detection biomarkers are lacking for …

Pan-cancer analysis of the characteristics of LY96 in prognosis and immunotherapy across human cancer

K Nie, J Li, L Peng, M Zhang, W Huang - Frontiers in molecular …, 2022 - frontiersin.org
Lymphocyte antigen 96 (LY96) is implicated in tumorigenesis by modulating host immunity.
However, an integrated pan-cancer analysis of LY96 in prognosis and immunotherapy …

Integrative approaches based on genomic techniques in the functional studies on enhancers

Q Wang, J Zhang, Z Liu, Y Duan… - Briefings in …, 2024 - academic.oup.com
With the development of sequencing technology and the dramatic drop in sequencing cost,
the functions of noncoding genes are being characterized in a wide variety of fields (eg …

Validation of the DNA Methylation Landscape of TFF1/TFF2 in Gastric Cancer

Z Qian, Y Jiang, C Shou, J Yu, D Huang, H Xie, L Zhou… - Cancers, 2022 - mdpi.com
Simple Summary The members of the TFF family have been illustrated to be tumor
suppressor genes in various malignancies. In this study, we first identified that TFF1/TFF2 …

Differential DNA methylation profiles in patients with temporal lobe epilepsy and hippocampal sclerosis ILAE type I

W Zhang, H Wang, B Liu, M Jiang, Y Gu, S Yan… - Journal of Molecular …, 2021 - Springer
Hippocampal sclerosis (HS) is one of the most prevalent pathological types of temporal lobe
epilepsy (TLE), and it significantly affects patient prognoses. The methylation of DNA plays …