Progression of chronic kidney disease: can it be prevented or arrested?

BL Jaber, NE Madias - The American journal of medicine, 2005 - Elsevier
Chronic kidney disease constitutes a highly prevalent health problem worldwide. Left
untreated, it progresses inexorably to greater levels of severity at variable rates. The morbid …

Beneficial role of sulfated polysaccharides from edible seaweed Fucus vesiculosus in experimental hyperoxaluria

CK Veena, A Josephine, SP Preetha, P Varalakshmi - Food Chemistry, 2007 - Elsevier
Sulfated polysaccharides from marine algae are known to possess numerous properties of
pharmacological importance. The present study is an attempt to evaluate the efficacy of the …

[PDF][PDF] Anti-proteinuric effects of glycosaminoglycan-based drugs

TJ Wijnhoven, JF Lensen, AL Rops… - Curr Opin Mol …, 2007 - researchgate.net
Heparan sulfate (HS) is a member of the family of glycosaminoglycans (GAGs) that is
generally bound to a core protein to form a proteoglycan (PG). HSPGs may be cell …

A study of unfractionated and low molecular weight heparins in a model of cholestatic liver injury in the rat

OME Abdel-Salam, AR Baiuomy, A Ameen… - Pharmacological …, 2005 - Elsevier
Forty-eight rats with biliary obstruction induced by double ligation and section of the
common bile duct were randomly and blindly assigned to receive subcutaneous injection of …

Tomato-oleoresin supplement prevents doxorubicin-induced cardiac myocyte oxidative DNA damage in rats

ALA Ferreira, DMF Salvadori… - … /Genetic Toxicology and …, 2007 - Elsevier
Doxorubicin (DOX) is an efficient chemotherapeutic agent used against several types of
tumors; however, its use is limited due to severe cardiotoxicity. Since it is accepted that …

Effect of lycopene on doxorubicin‐induced cardiotoxicity: An echocardiographic, histological and morphometrical assessment

AL Anjos Ferreira, RM Russell, N Rocha… - Basic & clinical …, 2007 - Wiley Online Library
Doxorubicin is an excellent chemotherapeutic agent utilized for several types of cancer but
the irreversible doxorubicin‐induced cardiac damage is the major limitation for its use …

Lipoic acid ameliorates adriamycin-induced testicular mitochondriopathy

C Prahalathan, E Selvakumar, P Varalakshmi - Reproductive Toxicology, 2005 - Elsevier
Adriamycin (ADR), an anthracycline antibiotic, which is widely used as an antineoplastic
drug in the treatment of various solid tumors, has been shown to induce reproductive …

Doxorubicin as an antioxidant: maintenance of myocardial levels of lycopene under doxorubicin treatment

ALA Ferreira, KJ Yeum, LS Matsubara… - Free Radical Biology …, 2007 - Elsevier
The mechanism of doxorubicin-induced cardiotoxicity remains controversial. Wistar rats (n=
96) were randomly assigned to a control (C), lycopene (L), doxorubicin (D), or doxorubicin+ …

Protective effect of vitamins c and e on malathion-induced nephrotoxicity in male rats

F Uzun, Y Kalender - Gazi University Journal of Science, 2011 - dergipark.org.tr
The male Wistar rats were given malathion and/or vitamin C+ vitamin E daily via gavage for
4 weeks. When malathion-, vitamins C+ E plus malathion-treated groups were compared to …

[HTML][HTML] The preventive effect of low molecular weight heparin on CCL4-induced necrosis and apoptosis in rat liver

A Kukner, F Tore, T Firat, EH Terzi, H Oner… - Annals of hepatology, 2010 - Elsevier
Introduction. Heparin having anti-inflammatory and anti-fibrotic properties may have
therapeutic effect on liver injury. The present study investigated the effect of low molecular …