Wolbachia-Virus interactions and arbovirus control through population replacement in mosquitoes

TH Ant, MV Mancini, CJ McNamara… - … and Global Health, 2023 - Taylor & Francis
Following transfer into the primary arbovirus vector Aedes aegypti, several strains of the
intracellular bacterium Wolbachia have been shown to inhibit the transmission of dengue …

Holobiont perspectives on tripartite interactions among microbiota, mosquitoes, and pathogens

R Zheng, Q Wang, R Wu, PN Paradkar… - The ISME …, 2023 - academic.oup.com
Mosquito-borne diseases like dengue and malaria cause a significant global health burden.
Unfortunately, current insecticides and environmental control strategies aimed at the vectors …

Releasing incompatible males drives strong suppression across populations of wild and Wolbachia-carrying Aedes aegypti in Australia

NW Beebe, D Pagendam, BJ Trewin… - Proceedings of the …, 2021 - National Acad Sciences
Releasing sterile or incompatible male insects is a proven method of population
management in agricultural systems with the potential to revolutionize mosquito control …

[HTML][HTML] A decade of stability for wMel Wolbachia in natural Aedes aegypti populations

PA Ross, KL Robinson, Q Yang, AG Callahan… - PLoS …, 2022 - journals.plos.org
Mosquitoes carrying Wolbachia endosymbionts are being released in many countries for
arbovirus control. The wMel strain of Wolbachia blocks Aedes-borne virus transmission and …

Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico

A Martín-Park, A Che-Mendoza… - PLOS Neglected …, 2022 - journals.plos.org
Background The combination of Wolbachia-based incompatible insect technique (IIT) and
radiation-based sterile insect technique (SIT) can be used for population suppression of …

A standalone incompatible insect technique enables mosquito suppression in the urban subtropics

Q Zeng, L She, H Yuan, Y Luo, R Wang, W Mao… - Communications …, 2022 - nature.com
The strong suppression of Aedes albopictus on two Guangzhou islands in China has been
successfully achieved by releasing males with an artificial triple-Wolbachia infection …

Environmental factors influence the local establishment of Wolbachia in Aedes aegypti mosquitoes in two small communities in central Vietnam

NT Hien, DD Anh, NH Le, NT Yen… - Gates Open …, 2022 - pmc.ncbi.nlm.nih.gov
Background: The wMel strain of Wolbachia has been successfully introduced into Aedes
aegypti mosquitoes and subsequently shown to reduce transmission of dengue and other …

Temperature effects on cellular host-microbe interactions explain continent-wide endosymbiont prevalence

MTJ Hague, JD Shropshire, CN Caldwell, JP Statz… - Current Biology, 2022 - cell.com
Endosymbioses influence host physiology, reproduction, and fitness, but these relationships
require efficient microbe transmission between host generations to persist. Maternally …

Gene Drive and Symbiont Technologies for Control of Mosquito-Borne Diseases

GH Wang, A Hoffmann… - Annual Review of …, 2024 - annualreviews.org
Mosquito-borne diseases, such as dengue and malaria, pose a significant burden to global
health. Current control strategies with insecticides are only moderately effective. Scalable …

Developing Wolbachia-based disease interventions for an extreme environment

PA Ross, S Elfekih, S Collier, MJ Klein, SS Lee… - PLoS …, 2023 - journals.plos.org
Aedes aegypti mosquitoes carrying self-spreading, virus-blocking Wolbachia bacteria are
being deployed to suppress dengue transmission. However, there are challenges in …