Autophagy is an intracellular self-degradative mechanism which responds to cellular
conditions like stress or starvation and plays a key role in regulating cell metabolism, energy …

Autophagy is a catabolic process for degrading dysfunctional proteins and organelles, and
closely associated with cancer cell survival under therapeutic, metabolic stress, hypoxia …

Growth factor-induced activation of protein kinase-B (PKB), also known as AKT, induces pro-
survival signaling and inhibits activation of pro-apoptotic signaling molecules including the …

Melanoma is one of the most aggressive forms of skin cancer and is characterized by high
metastatic potential. Despite improvements in early diagnosis and treatment, the mortality …

In spite of adjuvant chemotherapy, a significant fraction of patients with localized breast
cancer (BC) relapse after optimal treatment. We determined the occurrence of cytoplasmic …

Phenothiazines (PTZs) have been used for the antipsychotic drugs for centuries. However,
some of these PTZs have been reported to exhibit antitumor effects by targeting various …

Although numerous bibliometric studies have examined various aspects of cancer research,
the landscape of scientific studies focusing on natural products in cancer research has not …

The extracts of different parts of neem tree (Azadirachta indica) have been well documented
for its pharmacological or medicinal properties and their wide applications by indigenous …

Autophagy is a cell survival mechanism hijacked by advanced tumors to endure a rough
microenvironment. Late autophagy inhibitors such as (hydroxy) chloroquine have been used …

Secondary metabolites are the unique faction of compounds, produced by plants to protect
itself against the various biotic and abiotic factors (diseases, pests, pathogens, herbivores …