Lead (Pb) is a ubiquitous environmental pollutant and a potent toxic compound. Humans are
exposed to Pb through inhalation, ingestion, and skin contact via food, water, tobacco …

Pregnancy may be the most nutritionally sensitive stage in the life cycle, and improved
metabolic health during gestation and early postnatal life can reduce the risk of chronic …

Metabolic regulation plays important roles in embryo development and uterine receptivity
during early pregnancy, ultimately influencing pregnancy efficiency in mammals. The …

Placental insufficiency is associated with reduced oxygen and nutrient supply to the fetus,
which may result in fetal growth restriction (FGR). In an attempt to cope with the hostile …

Lipids are key molecules in various biological processes, thus their quantification is a crucial
point in a lot of studies and should be taken into account in lipidomics development. This …

High-altitude (HA) hypoxia lowers uterine artery (UtA) blood flow during pregnancy and birth
weight. Adenosine monophosphate kinase (AMPK) activation has selective, uteroplacental …

(1) Background: Intrauterine growth restriction (IUGR) involves metabolic changes that may
be responsible for an increased risk of metabolic and cardiovascular diseases in adulthood …

Gestational hyperandrogenism adversely impacts offspring health. Using an ovine model,
we found that prenatal testosterone (T) excess adversely affects growth and cardiometabolic …

Background Fetal growth restriction (FGR) affects 7–10% of all pregnancies resulting in a
higher risk of perinatal morbidity and mortality, long-term disabilities, and cognitive …

Preeclampsia (PE) and fetal growth restriction (FGR) are both placenta-mediated disorders
with unclear pathogenesis. Metabolomics of maternal and fetal pairs might help in …