High-content analysis (HCA) combines automated microscopy and automated image
analysis to quantify complex cellular anatomy and biochemistry objectively, accurately and …

Background Nonalcoholic fatty liver disease (NAFLD) is a known outcome of
hepatosteatosis. Free fatty acids (FFA) induce the unfolded protein response (UPR) or …

Background. Steatotic livers are increasingly common in the donor population. Cold storage
of steatotic livers exacerbates ischemia-reperfuson injury and risks primary nonfunction and …

Obesity is one of major risk factors increasing chronic diseases including type II diabetes,
cardiovascular diseases, and hypertension. The effects of epigallocatechin gallate (EGCG) …

Aging and adiposity are associated with chronic low‐grade inflammation, which underlies
the development of obesity‐associated complications, including type 2 diabetes mellitus …

The increasing availability and performance of automated scientific equipment in the past
decades have brought about a revolution in the biological sciences. The ease with which …

Bone marrow–derived mesenchymal stem cells (MSCs) are a common precursor of both
adipocytes and osteoblasts. While it is appreciated that PPARγ regulates the balance …

Obesity is associated with the growth and expansion of adipocytes which could be
decreased via several mechanisms. Cissus Quadrangularis (CQ) extract has been shown to …

In vitro differentiating adipocytes are sensitive to liquid manipulations and have the tendency
to float. Assessing adipocyte differentiation using current microscopy techniques involves …

One hallmark of obesity is adipocyte hypertrophy and hyperplasia. To gain novel insights
into adipose biology and therapeutics, there is a pressing need for a robust, rapid, and …