Signaling pathways that mediate the normal functions of growth factors are commonly
subverted in cancer. Oncogenes identified by a variety of approaches have been shown to …

The functions and biochemical mechanisms involved in cell signalling by phosphoinositide
breakdown are now well defined[l-3]. drolysis of polyphosphoinositides (PI) yieI motes rhe …

Peptides, as neurotransmitters, neuromodulators, and hormones, influence a multitude of
physiological processes by signal transduction mediated through receptors. In addition …

G protein‐coupled receptor (GPCR) agonists, including neurotransmitters, hormones,
chemokines, and bioactive lipids, act as potent cellular growth factors and have been …

Tubular reabsorption of filtered sodium is quantitatively the main contribution of kidneys to
salt and water homeostasis. The transcellular reabsorption of sodium proceeds by a two …

PROTEIN-TYROSINE kinases (PTKs) and protein-tyrosine phosphatases (PTPs) are key
enzymes in signal-transduction pathways for a wide range of cellular processes1, 2. PTKs …

Vascular endothelial growth factor (VEGF) stimulated the tyrosine phosphorylation of
multiple components in confluent human umbilical vein endothelial cells (HUVECs) …

The interaction of cells with extracellular matrix proteins plays a critical role in a variety of
biological processes. Recent studies suggest that cell-matrix interactions mediated by …

This article reviews research which addresses the metabolism and functions of a recently
discovered family of membrane phospholipids, the 3-phosphorylated phosphoinositides. It is …

Lysophosphatidic acid (LPA) and bombesin rapidly stimulate the formation of focal
adhesions and actin stress fibres in serum‐starved Swiss 3T3 fibroblasts, a process …