In this review, we summarize the current knowledge about the membranous replication
factories of members of plus-strand (+) RNA viruses. We discuss primarily the architecture of …

Viruses have evolved complex and dynamic interactions with their host cell. In recent years
we have gained insight into the expanding roles for host lipids in the virus life cycle. In …

Plus-strand RNA virus replication occurs in tight association with cytoplasmic host cell
membranes. Both, viral and cellular factors cooperatively generate distinct organelle-like …

The endoplasmic reticulum (ER) is the largest intracellular organelle. It forms a complex
network of continuous sheets and tubules, extending from the nuclear envelope (NE) to the …

Positive strand RNA viruses replicate in the cytoplasm of infected cells and induce
intracellular membranous compartments harboring the sites of viral RNA synthesis. These …

Many viruses reorganise cellular membrane compartments and the cytoskeleton to generate
subcellular microenvironments called virus factories or 'viroplasm'. These create a platform …

Hepatitis C virus (HCV) is a positive-strand RNA virus of the Flaviviridae family and a major
cause of liver disease worldwide. HCV replicates in the cytoplasm, and the synthesis of viral …

Understanding Viruses continues to set the standard for the fundamentals of virology. This
classic textbook combines molecular, clinical, and historical aspects of human viral diseases …

Replication and assembly of many viruses occur in specific intracellular compartments
known as 'virus factories'. Our knowledge of the biogenesis and architecture of these unique …

Virus-induced membrane structures support the assembly and function of positive-strand
RNA virus replication complexes. The replicase proteins of arteriviruses are associated with …