Randomly barcoded transposon mutant libraries for gut commensals I: Strategies for efficient library construction

S Tripathi, CGP Voogdt, SO Bassler, M Anderson… - Cell Reports, 2024 - cell.com
Randomly barcoded transposon mutant libraries are powerful tools for studying gene
function and organization, assessing gene essentiality and pathways, discovering potential …

[HTML][HTML] Harnessing gut microbial communities to unravel microbiome functions

S Giri, H Shi, A Typas, KC Huang - Current Opinion in Microbiology, 2025 - Elsevier
The gut microbiome impacts human health in direct and indirect ways. While many
associations have been discovered between specific microbiome compositions and …

Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics

N Sakenova, E Cacace, A Orakov, F Huber… - Nature …, 2025 - nature.com
By acquiring or evolving resistance to one antibiotic, bacteria can become cross-resistant to
a second antibiotic, which further limits therapeutic choices. In the opposite scenario, initial …

Adhesin RadD: the secret weapon of Fusobacterium nucleatum

D Jia, S Chen - Gut Microbes, 2024 - Taylor & Francis
Fusobacterium nucleatum can promote colorectal cancer (CRC) development through a
variety of virulence proteins. Zhang et al. recently identified an adhesin RadD, for …

Off-purpose activity of industrial and agricultural chemicals against human gut bacteria

AE Lindell, S Kamrad, I Roux, S Krishna… - bioRxiv, 2024 - biorxiv.org
Contamination by industrial and agricultural chemicals like pesticides are a cause of great
concern due to the risk to human and environmental health. While these chemicals are often …

Identifying Xanthomonas recruitment genes in the soil-borne legacy

E Klaasen - 2024 - studenttheses.uu.nl
The plant microbiome can help the plant mitigate biotic stress. Hpa associated microbiota
(HAM) are beneficial bacteria for which it is proven that Arabidopsis thaliana can actively …