Obesity and cholesterol gallstone disease (GSD) are frequently coexisting diseases;
therefore and considering the current worldwide obesity epidemics, a precise understanding …

Synopsis: Ursodeoxycholic acid 1 is the 7β-hydroxy epimer of chenodeoxycholic acid and is
normally present in only trace amounts in the bile. Oral administration of pharmacological …

Cholesterol gallstone disease is initiated in a liver which produces abnormal bile with
excess cholesterol relative to bile salts and phospholipid. To define the responsible …

Background & Aims: Results concerning an association between cholecystectomy and right-
sided colon cancer are inconsistent. Little is known about the relation between …

OBJECTIVES: Other than weight-related conditions, risk factors for non-alcoholic fatty liver
disease (NAFLD) are not well defined. We investigated the association of gallstones and …

Background This study examined the association of cholelithiasis post-cholecystectomy with
subsequent cancers and evaluated the risk of cancer in patients with both cholelithiasis and …

Gälman C, Angelin B, Rudling M.(Karolinska Institutet at Karolinska University Hospital,
Stockholm). Pronounced variation in bile acid synthesis in humans is related to gender …

Background and rationale for the study. FGF19/15 is a gut-derived hormone presumably
governing bile acid (BA) synthesis and gallbladder (GB) refilling. FGF19 mRNA is present in …

AIM: To investigate the relationship between gallstone disease and nonalcoholic fatty liver
disease (NAFLD) in a large Asian population. METHODS: A cross-sectional study including …

Methods: Plasma BA levels and composition and fibroblast growth factor (FGF)-19 levels
were measured during fasting and in response to an oral glucose load before and at 1 …