Development of chemotherapeutic treatment modalities resulted in a dramatic increase in
the survival of children with many types of cancer. Still, in case of some pediatric cancer …

BACKGROUND: The objectives of this study were to measure the incidence of sarcomas,
including viscerally sited tumors that are not reported in cancer statistics, and to draw …

Rhabdomyosarcoma (RMS) represents the most common soft tissue sarcoma in infants and
children and the third most common pediatric solid tumor, accounting for 5% to 15% of all …

Purpose The aim of the present study was to elucidate the clinico-pathological
characteristics of female patients with lower genital tract rhabdomyosarcoma (RMS) stratified …

Interleukins-6 (IL-6)/GP130 signaling pathway represents a promising target for cancer
therapy due to its critical role in survival and progression of multiple types of cancer. We …

Glyphosate-based herbicides (GBHs) have been associated with endocrine disrupting
effects on reproductive organs. We examined whether postnatal exposure to GBH affects …

Background The relevance of estrogen receptor (ER) expression in pancreatic ductal
adenocarcinoma (PDAC) is largely unknown. Clinical trials targeting ER with selective …

Objective To review the pathophysiology of rhabdomyomas and the emerging option of
prenatal treatment of fetal cardiac rhabdomyomas. Methods We present a case of fetal …

Optimal management of rhabdomyosarcoma requires establishing the correct pathologic
diagnosis, histologic sub-type, primary site, extent of disease (Stage), and extent of resection …

Recent studies have shown a significant involvement of insulin-like growth factor (IGF)
signaling components in the pathogenesis of rhabdomyosarcoma (RMS). Furthermore, there …