Understanding the noncovalent interactions (NCIs) among the residues of proteins and
nucleic acids, and between drugs and proteins/nucleic acids, etc., has extraordinary …

The halogen bond occurs when there is evidence of a net attractive interaction between an
electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic …

Supramolecular chemistry is “the chemistry of the intermolecular bond, covering the
structures and functions of the entities formed by association of two or more chemical …

Halogen bonding is a noncovalent interaction similar to hydrogen bonding, which is based
on electrophilic halogen substituents. Hydrogen‐bonding‐based organocatalysis is a well …

In the field of noncovalent interactions a new paradigm has recently become popular. It
stems from the analysis of molecular electrostatic potentials and introduces a label, which …

The σ-hole and π-hole are the regions with positive surface electrostatic potential on the
molecule entity; the former specifically refers to the positive region of a molecular entity …

Halogen bonding has been known in material science for decades, but until recently,
halogen bonds in protein–ligand interactions were largely the result of serendipitous …

Halogen bonding is an emerging noncovalent interaction for constructing supramolecular
assemblies. Though similar to the more familiar hydrogen bonding, four primary differences …

A halogen bond is a highly directional, electrostatically-driven noncovalent interaction
between a region of positive electrostatic potential on the outer side of the halogen X in a …

Halogen bonding is a noncovalent interaction that is receiving rapidly increasing attention
because of its significance in biological systems and its importance in the design of new …