Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases
The eukaryotic transcription apparatus synthesizes a staggering diversity of RNA molecules.
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
Recruitment of RNA polymerase III to its target promoters
L Schramm, N Hernandez - Genes & development, 2002 - genesdev.cshlp.org
A key step in retrieving the information stored in the complex genomes of eukaryotes
involves the identification of transcription units and, more specifically, the recognition of …
involves the identification of transcription units and, more specifically, the recognition of …
Efficiency and inheritance of targeted mutagenesis in maize using CRISPR-Cas9
CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated
proteins) is an adaptive immune system in bacteria and archaea to defend against invasion …
proteins) is an adaptive immune system in bacteria and archaea to defend against invasion …
Survey and summary transcription by RNA polymerases I and III
MR Paule, RJ White - Nucleic acids research, 2000 - academic.oup.com
The task of transcribing nuclear genes is shared between three RNA polymerases in
eukaryotes: RNA polymerase (pol) I synthesises the large rRNA, pol II synthesises mRNA …
eukaryotes: RNA polymerase (pol) I synthesises the large rRNA, pol II synthesises mRNA …
Accelerated homologous recombination and subsequent genome modification in Drosophila
LA Baena-Lopez, C Alexandre, A Mitchell… - …, 2013 - journals.biologists.com
Gene targeting by 'ends-out'homologous recombination enables the deletion of genomic
sequences and concurrent introduction of exogenous DNA with base-pair precision without …
sequences and concurrent introduction of exogenous DNA with base-pair precision without …
Spliceosomal RNA U6 is remarkably conserved from yeast to mammals
DA Brow, C Guthrie - Nature, 1988 - nature.com
The small nuclear RNA U6 and its gene have been isolated from yeast. In striking contrast to
other yeast spliceosomal RNAs, U6 is very similar in size, sequence and structure to its …
other yeast spliceosomal RNAs, U6 is very similar in size, sequence and structure to its …
S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors
GA Kassavetis, BR Braun, LH Nguyen, EP Geiduschek - Cell, 1990 - cell.com
The S. cerevisiae RNA polymerase Ill (pol III) transcription factor TFIIIB binds to DNA
upstream of the transcription start site of the SUP4 tRNATyr gene in a TFIIIC dependent …
upstream of the transcription start site of the SUP4 tRNATyr gene in a TFIIIC dependent …
The life of U6 small nuclear RNA, from cradle to grave
AL Didychuk, SE Butcher, DA Brow - Rna, 2018 - rnajournal.cshlp.org
Removal of introns from precursor messenger RNA (pre-mRNA) and some noncoding
transcripts is an essential step in eukaryotic gene expression. In the nucleus, this process of …
transcripts is an essential step in eukaryotic gene expression. In the nucleus, this process of …
Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III.
E Gottlieb, JA Steitz - The EMBO journal, 1989 - embopress.org
We have tested the hypothesis that the mammalian La protein, which appears to be required
for accurate and efficient RNA polymerase III transcription, is a transcription termination …
for accurate and efficient RNA polymerase III transcription, is a transcription termination …
Inhibition of viral gene expression by the catalytic RNA subunit of RNase P from Escherichia coli.
F Liu, S Altman - Genes & development, 1995 - genesdev.cshlp.org
The catalytic RNA subunit (M1 RNA) of RNase P from Escherichia coli has been converted
to an endoribonuclease that specifically cleaves the mRNA that encodes thymidine kinase …
to an endoribonuclease that specifically cleaves the mRNA that encodes thymidine kinase …