RNA viruses interact with a wide range of cellular RNA-binding proteins (RBPs) during their life cycle. The prevalence of these host–virus interactions has been highlighted by new …
S Zhao, J Cordes, KM Caban, MJ Götz… - Molecular cell, 2023 - cell.com
Reactive aldehydes are abundant endogenous metabolites that challenge homeostasis by crosslinking cellular macromolecules. Aldehyde-induced DNA damage requires repair to …
AS Rahmanto, CJ Blum, C Scalera, JB Heidelberger… - Molecular Cell, 2023 - cell.com
Reactive aldehydes are produced by normal cellular metabolism or after alcohol consumption, and they accumulate in human tissues if aldehyde clearance mechanisms are …
W Kamel, V Ruscica, A Embarc-Buh, ZR de Laurent… - Molecular Cell, 2024 - cell.com
RNA is a central molecule for viruses; however, the interactions that viral RNA (vRNA) establishes with the host cell is only starting to be elucidated. Here, we determine the …
JI Perez-Perri, D Ferring-Appel, I Huppertz… - Nature …, 2023 - nature.com
Abstract System-wide approaches have unveiled an unexpected breadth of the RNA-bound proteomes of cultured cells. Corresponding information regarding RNA-binding proteins …
J Aydin, A Gabel, S Zielinski, S Ganskih… - Nucleic Acids …, 2024 - academic.oup.com
RNA-protein interactions determine the cellular fate of RNA and are central to regulating gene expression outcomes in health and disease. To date, no method exists that is able to …
S Rehman, S Bahadur, W Xia, C Runan, M Ali… - International Journal of …, 2024 - Elsevier
RNA-binding proteins (RBPs) are essential for cellular functions by attaching to RNAs, creating dynamic ribonucleoprotein complexes (RNPs) essential for managing RNA …
CP Sarnowski, M Bikaki, A Leitner - Structure, 2022 - cell.com
Cross-linking and mass spectrometry (XL-MS) workflows represent an increasingly popular technique for low-resolution structural studies of macromolecular complexes. Cross-linking …