Small extracellular vesicles (sEVs) are 30–200 nm nanovesicles enriched with unique
cargoes of nucleic acids, lipids, and proteins. sEVs are released by all cell types and have …

Nanoscale extracellular vesicles (EVs), consisting of exomers, exosomes and microvesicles/
ectosomes, have been extensively investigated in the last 20 years, although their biological …

RNA-based therapeutics are highly promising for the treatment of numerous diseases, by
their ability to tackle the genetic origin in multiple possible ways. RNA molecules are …

The retina encompasses a network of neurons, glia and epithelial and vascular endothelia
cells, all coordinating visual function. Traditionally, molecular information exchange in this …

The mechanisms underlying retinal development have not been completely elucidated.
Extracellular vesicles (EVs) are novel essential mediators of cell-to-cell communication with …

Cell‐cell interactions in the central nervous system are based on the release of molecules
mediating signal exchange and providing structural and trophic support through vesicular …

Exosomes are nano-sized lipid vesicles that are produced by all eukaryotic cells, and they
typically range in size from 30 to 150 nm. Exosomes were discovered almost 40 years ago; …

Diabetic retinopathy (DR) is a complex, progressive, and heterogenous retinal degenerative
disease associated with diabetes duration. It is characterized by glial, neural, and …

Introduction Diabetic Retinopathy (DR) is a potentially blinding retinal disorder that develops
through the pathogenesis of diabetes. The lack of disease predictors implies a poor …

Inherited and non-inherited retinopathies can affect distinct cell types, leading to progressive
cell death and visual loss. In the last years, new approaches have indicated exciting …