Spermatogenesis is a complex and dynamic cellular differentiation process critical to male
reproduction and sustained by spermatogonial stem cells (SSCs). Although patterns of gene …

Sertoli cells regulate male germ cell proliferation and differentiation and are a critical
component of the spermatogonial stem cell (SSC) niche, where homeostasis is maintained …

Mammalian spermatogenesis is a complex developmental program that transforms mitotic
testicular germ cells (spermatogonia) into mature male gametes (sperm) for production of …

Mammalian male germ cell development is a stepwise cell-fate transition process; however,
the full-term developmental profile of male germ cells remains undefined. Here, by …

Spermatogenesis is a classic model of cycling cell lineages that depend on a balance
between stem cell self-renewal for continuity and the formation of progenitors as the initial …

Buffalo bulls are backbone of Indian dairy industry, and the quality of semen donating bulls
determine the overall production efficiency of dairy farms. Seminal plasma harbor millions of …

Spermatogonial stem cells (SSCs) and progenitor spermatogonia encompass the
undifferentiated spermatogonial pool in mammalian testes. In rodents, this population is …

Because epigenetics is a critical component for gene expression, the hypothesis was tested
that DNA methylation alterations are dynamic and continually change throughout …

Spermatogonial stem cells (SSCs) sustain spermatogenesis by balancing self-renewal and
initiation of differentiation to produce progenitor spermatogonia committed to forming sperm …

Reproductive suppression is an adaptive strategy in animal reproduction. The mechanism of
reproductive suppression has been studied in social animals, providing an essential basis …