The nicotinamide adenine dinucleotide phosphate hydrogen oxidase (NADPH oxidase or
NOX) plays a critical role in the inflammatory response and fibrosis in several organs such …

Abstract Background Second-generation antipsychotics (SGAs) are a mainstay therapy for
schizophrenia. SGA-treated patients present higher risk for weight gain, dyslipidemia and …

Abstract Traditional Chinese Medicine (TCM) has been widely used in the treatment of
various diseases for millennia. In the modernization process of TCM, TCM ingredient …

Abstract Ethnopharmacological relevance Baihe Wuyao decoction (BWD), a prescription of
Traditional Chinese Medicines, composed of Lilium brownii var. viridulum Baker.(Lilii …

Pueraria thomsonii Radix. as an important edible and medicinal plant in China, its effects
and mechanisms on alcoholic liver disease (ALD) remain unclear. Herein, we investigated …

Protein tyrosine phosphatase 1B (PTP1B) is a non-receptor tyrosine phosphatase best
known for its role in regulating insulin and leptin signalling. Recently, knowledge on the role …

Activation of oval cells (OCs) has been related to hepatocyte injury during chronic liver
diseases including non-alcoholic fatty liver disease (NAFLD). However, OCs plasticity can …

Olanzapine (OLA), a widely used second-generation antipsychotic (SGA), causes weight
gain and metabolic alterations when administered orally to patients. Recently, we …

Alcoholic liver disease (ALD) is a major health problem and a significant cause of liver-
related death. Currently, the mainstay for ALD therapy is alcohol abstinence highlighting the …

Fibrosis is a pathological result of a dysfunctional repair response to tissue injury and occurs
in several organs, including the lungs. Bryodulcosigenin (BDG) is a cucurbitane‐type …