Metabolism and atherogenic disease association of lysophosphatidylcholine

G Schmitz, K Ruebsaamen - Atherosclerosis, 2010 - Elsevier
Lysophosphatidylcholine (LPC) is a major plasma lipid that has been recognized as an
important cell signalling molecule produced under physiological conditions by the action of …

Modulation of enzymatic activities by n-3 polyunsaturated fatty acids to support cardiovascular health

RA Siddiqui, KA Harvey, GP Zaloga - The Journal of nutritional …, 2008 - Elsevier
Epidemiological evidence from Greenland Eskimos and Japanese fishing villages suggests
that eating fish oil and marine animals can prevent coronary heart disease. Dietary studies …

Potential of microalga Isochrysis galbana: Bioactivity and bioaccessibility

C Bonfanti, C Cardoso, C Afonso, J Matos, T Garcia… - Algal research, 2018 - Elsevier
The lipid composition and anti-inflammatory activity of the microalga Isochrysis galbana
were studied. Moreover, the influence of bioaccessibility on composition and bioactivity was …

Effect of ergosta-4, 6, 8 (14), 22-tetraen-3-one (ergone) on adenine-induced chronic renal failure rat: a serum metabonomic study based on ultra performance liquid …

YY Zhao, XL Cheng, JH Cui, XR Yan, F Wei, X Bai… - Clinica chimica acta, 2012 - Elsevier
BACKGROUND: Ergosta-4, 6, 8 (14), 22-tetraen-3-one (ergone) has been proven to prevent
the progression of renal injury and the subsequent renal fibrosis. We investigated the …

Anti‐fibrotic mechanisms of angiotensin AT2‐receptor stimulation

C Sumners, AA Peluso, AH Haugaard… - Acta …, 2019 - Wiley Online Library
The angiotensin AT2‐receptor is a main receptor of the protective arm of the renin‐
angiotensin system. Understanding of this unconventional G‐protein coupled receptor has …

Anti-inflammatory effects of Polygonum minus (Huds) extract (Lineminus™) in in-vitro enzyme assays and carrageenan induced paw edema

A George, S Chinnappan, M Chintamaneni… - … and alternative medicine, 2014 - Springer
Background The study was aimed to evaluate the anti-inflammatory activity of ethanolic and
aqueous extracts of Polygonum minus (Huds) using in vitro and in vivo approaches …

Lipidomic profiling reveals disruption of lipid metabolism in valproic acid-induced hepatotoxicity

S Xu, Y Chen, Y Ma, T Liu, M Zhao, Z Wang… - Frontiers in …, 2019 - frontiersin.org
Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs, as VPA-induced
hepatotoxicity is one of the most severe adverse reaction that can lead to death. The …

Metabolite modulation in human plasma in the early phase of acclimatization to hypobaric hypoxia

WT Liao, B Liu, J Chen, JH Cui, YX Gao, FY Liu, G Xu… - Scientific reports, 2016 - nature.com
The exposure of healthy subjects to high altitude represents a model to explore the
pathophysiology of diseases related to tissue hypoxia. We explored a plasma metabolomics …

Serum metabonomics study of chronic renal failure by ultra performance liquid chromatography coupled with Q-TOF mass spectrometry

L Jia, J Chen, P Yin, X Lu, G Xu - Metabolomics, 2008 - Springer
A metabonomics technique based on ultra-performance liquid chromatography (UPLC)
coupled with Q-TOF mass spectrometry was employed to investigate the sera from 32 …

Ergothioneine Ameliorates Liver Fibrosis by Inhibiting Glycerophospholipids Metabolism and TGF‐β/Smads Signaling Pathway: Based on Metabonomics and Network …

Y Mao, Z Xie, X Zhang, Y Fu, X Yu… - Journal of Applied …, 2024 - Wiley Online Library
Ergothioneine (EGT) is a diet‐derived natural sulfur‐containing amino acid that exhibits
strong anti‐oxidant and anti‐inflammation activities. Oxidative stress and chronic …