Clustered randomly interspaced short palindromic repeats (CRISPRs) and its associated
endonuclease protein, ie, Cas9, have been discovered as an immune system in bacteria …

Glioblastoma multiforme (GBM) is the deadliest brain tumor with a poor prognosis and
limited therapeutic options. Temozolomide (TMZ) is the first-line chemotherapeutic agent …

In the present era of “Diabetic Pandemic”, peptide-based therapies have generated
immense interest however, are facing odds due to inevitable limitations like stability, delivery …

Delivering macromolecules across the skin poses challenges due to the barrier properties of
stratum corneum. Different strategies have been reported to cross this barrier, such as …

Eye-related diseases, specifically retinal dystrophy (RD) conditions, are the leading cause of
blindness worldwide. Gene addition, regulation, or editing could potentially treat such …

CRISPR/Cas9 has proven its accuracy and precision for gene editing by making a double‐
strand break at the predetermined site. Despite being a mainstream gene editing tool …

Psoriasis is a chronic skin disease characterized by inflammation caused by the activation of
the immune system. Although the etiology of psoriasis is still unknown, the crosstalk …

This chapter examines the concept of biomimicry in drug delivery and delves into the
employed rational design strategies. It highlights the necessity for inventive approaches that …