Continuous manufacturing and Green Chemistry, are two promising approaches to
synthesis with underutilized potential that are gaining traction by the wider pharmaceutical …

Abstract The Food and Drug Administration (FDA) regulates pharmaceutical drug products
to ensure a continuous supply of high-quality drugs in the USA. Continuous processing has …

Continuous drug product manufacturing is slowly being implemented in the pharmaceutical
industry. Although the benefits related to the quality and cost of continuous manufacturing …

This review traces current applications of the residence time theory in various solid unit
operations. Besides reviewing recent experimental and simulation studies in the literature …

Continuous processing in pharmaceutical manufacturing is a relatively new approach that
has generated significant attention. While it has been used for decades in other industries …

We propose a generalization of the Weibull dissolution model, referred to as generalized
Weibull dissolution model, that seamlessly captures all three fractional dissolution rates …

This study presents a framework for process and product development on a continuous
direct compression manufacturing platform. A challenging sustained release formulation …

Manufacturing of powder-based products is a focus of increasing research in the recent
years. The main reason is the lack of predictive process models connecting process …

Blend uniformity is a critical quality attribute in continuous pharmaceutical manufacturing.
However, its measurement is challenging due to the difficulty and inaccessibility of sampling …

This paper focuses on two aspects of continuous powder mixing, namely characterizing the
effects of material properties on the bulk powder flow behavior, and developing continuous …