Effects of l-carnitine supplementation on weight loss and body composition: A systematic review and meta-analysis of 37 randomized controlled clinical trials with dose …

N Talenezhad, M Mohammadi… - Clinical nutrition …, 2020 - Elsevier
Background and aim Clinical evidence which investigated the effects of l-carnitine, a vitamin-
like substance, on weight loss had led to inconsistent results. This study therefore aimed to …

Mitochondria: a new therapeutic target in chronic kidney disease

S Granata, A Dalla Gassa, P Tomei, A Lupo… - Nutrition & …, 2015 - Springer
Cellular metabolic changes during chronic kidney disease (CKD) may induce higher
production of oxygen radicals that play a significant role in the progression of renal damage …

Randomized phase III clinical trial of a combined treatment with carnitine+ celecoxib±megestrol acetate for patients with cancer-related anorexia/cachexia syndrome

C Madeddu, M Dessì, F Panzone, R Serpe, G Antoni… - Clinical nutrition, 2012 - Elsevier
BACKGROUND & AIMS: A phase III, randomized non-inferiority study was carried out to
compare a two-drug combination (including nutraceuticals, ie antioxidants) with carnitine+ …

Antiinflammatory effects of L-carnitine supplementation (1000 mg/d) in coronary artery disease patients

BJ Lee, JS Lin, YC Lin, PT Lin - Nutrition, 2015 - Elsevier
Objective Inflammation mediators have been recognized as risk factors for the pathogenesis
of coronary artery disease (CAD). The purpose of this study was to investigate the effect of l …

Significance of levocarnitine treatment in dialysis patients

H Takashima, T Maruyama, M Abe - Nutrients, 2021 - mdpi.com
Carnitine is a naturally occurring amino acid derivative that is involved in the transport of
long-chain fatty acids to the mitochondrial matrix. There, these substrates undergo β …

The frequency of periodontitis in end-stage renal disease on hemodialysis in a sample of Egyptian population: Multi-center clinical cross-sectional study

A Abou-Bakr, RR Hussein, E Khalil, E Ahmed - BMC Oral Health, 2022 - Springer
Background There is a general assumption that periodontal disease is highly prevalent
among patients with chronic renal failure undergoing hemodialysis. The aim of the study to …

Carnitine palmitoyltransferase system: a new target for anti-inflammatory and anticancer therapy?

M Wang, K Wang, X Liao, H Hu, L Chen… - Frontiers in …, 2021 - frontiersin.org
Lipid metabolism involves multiple biological processes. As one of the most important lipid
metabolic pathways, fatty acid oxidation (FAO) and its key rate-limiting enzyme, the carnitine …

Effects of l-carnitine infusions on inflammatory and nutritional markers in haemodialysis patients

M Duranay, H Akay, FM Yilmaz, M Şeneş… - Nephrology Dialysis …, 2006 - academic.oup.com
Background. Carnitine loss through dialysis membranes is shown to be related to the lack of
carnitine in long-term haemodialysis patients. It has been previously reported that …

Potential roles of mitochondrial cofactors in the adjuvant mitigation of proinflammatory acute infections, as in the case of sepsis and COVID-19 pneumonia

G Pagano, C Manfredi, FV Pallardó, A Lyakhovich… - Inflammation …, 2021 - Springer
Background The mitochondrial cofactors α-lipoic acid (ALA), coenzyme Q10 (CoQ10) and
carnitine (CARN) play distinct and complementary roles in mitochondrial functioning, along …

Mechanisms underlying the anti-wasting effect of l-carnitine supplementation under pathologic conditions: evidence from experimental and clinical studies

R Ringseis, J Keller, K Eder - European journal of nutrition, 2013 - Springer
Purpose Loss of skeletal muscle mass, also known as muscle wasting or muscle atrophy, is
a common symptom of several chronic diseases, such as cancer and infectious diseases …