2015-05-21 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …

Surface-modi? ed microparticles and methods of making and using such particles are
disclosed. The surface modi? ed microparticles include a preformed or core microparticle …

This investigation relates to a two-step formulation development technique-synthesis of
sterically stabilized drug microcrystals followed by direct surface modification by sequential …

Disclosed herein is a multilayer film comprising two or more layers of polyelectrolytes,
wherein adjacent layers comprise oppositely charged polyelectrolytes. A first layer …

Disclosed herein are films, coatings and microcapsules comprising polypeptides. A thin film,
for example, comprises a plurality of layers of polypeptides, the layers comprising alternating …

Inventor: Michael N. Helmus, Worcester, MA (US) The present invention is directed to the
formation of struc tures in situ through the principles of ligand binding. These structures are …

The present disclosure relates to compositions of methods of making and compositions
Small compositions of particles of an active agent. In accordance with the method of …

Compositions of spherical insulin particles having improved pulmonary application
potentials and methods of forming and using these compositions are disclosed in the …

SUMMARY 0002 There are several aspects of the present disclosure. In one aspect, the
disclosure provides for microparticle compositions and methods for making the …

Disclosed herein are immunogenic compositions comprising a multilayer film comprising
two or more layers of polyelec trolytes, wherein adjacent layers comprise oppositely charged …