Background: Oestrogen receptor-negative (ER−) breast cancer is intrinsically sensitive to
chemotherapy. However, tumour response is often incomplete, and relapse occurs with high …

Importance Adjuvant therapy is an important and effective treatment for retinoblastoma.
However, there is a lack of head-to-head clinical trials comparing 3 vs 6 cycles of CEV …

Preferentially expressed antigen in melanoma (PRAME) is the best characterized member of
the PRAME family of leucine-rich repeat (LRR) proteins. Mammalian genomes contain …

Carboplatin is the most commonly used drug in the first-line treatment of human
retinoblastoma (RB), but its clinical application is greatly limited due to acquired drug …

Retinoblastoma (RB) is the most common primary intraocular cancer in children, and the
third most common cancer overall in infants. No molecular-targeted therapy for this lethal …

The present study aimed to explore the combined role of microRNA (miR)-34a, melanoma
antigen-A (MAGE-A) and p53 in altering the chemosensitivity of retinoblastoma (RB) cells …

Retinoblastoma is the most common intraocular malignancy during childhood. Currently,
there is no effective treatment for metastatic retinoblastoma. We investigated potential …

Purpose: Retinoblastoma is a malignant tumor of the developing retina that mostly occurs in
children. Our study aimed to investigate the effect of tripartite motif-containing protein 59 …

Purpose: The purpose of this paper was to investigate the expression and function of
Ubiquitin-conjugating enzyme 2T (UBE2T), a human E2 ubiquitin-conjugating enzyme, in …

Primary open-angle glaucoma (POAG) is the most common form of glaucoma. This condition
leads to optic nerve degeneration and eventually to blindness. Tobacco smoking, alcohol …