This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

For a blood-borne cancer therapeutic agent to be effective, it must cross the blood vessel
wall to reach cancer cells in adequate quantities, and it must overcome the resistance …

Porphyrins are organic compounds that continue to attract much theoretical interest, and
have been called the “pigments of life”. They have a wide role in photodynamic and …

Oncolytic viruses (OVs) infect, multiply, and finally remove tumor cells selectively, causing no
damage to normal cells in the process. Because of their specific features, such as, the ability …

The defining hallmark of stem cells is their ability to self-renew and maintain multipotency.
This capacity depends on the balance of complex signals in their microenvironment. Low …

Background Tumor associated fibroblasts (TAF), are essential for tumor progression
providing both a functional and structural supportive environment. TAF, known as activated …

Recent pre-clinical and clinical studies have shown that stem cell-based therapies hold
tremendous promise for the treatment of human disease. Mesenchymal stem cells (MSC) …

The poor prognosis of patients with aggressive and invasive cancers combined with toxic
effects and short half-life of currently available treatments necessitate development of more …

Introduction: Drug targeting to sites of tissue injury, tumor or infection with limited toxicity is
the goal for successful pharmaceutics. Immunocytes (including mononuclear phagocytes …

Mesenchymal stem cells (MSCs) are self-renewing, multipotent progenitor cells with
multilineage potential to differentiate into cell types of mesodermal origin, such as …