Background The proteome is a major source of therapeutic targets. We conducted a
proteome-wide Mendelian randomization (MR) study to identify candidate protein markers …

High-grade serous ovarian cancer (HGSOC) is the most lethal tumor of the female genital
tract. Despite extensive studies and the identification of some precursor lesions like serous …

Background Multiple myeloma (MM) is a severely debilitating and fatal B-cell neoplastic
disease. The discovery of disease-associated proteins with causal genetic evidence offers a …

Background: Predicting protein levels from genotypes for proteome-wide association studies
(PWAS) may provide insight into the mechanisms underlying cancer susceptibility. Methods …

Microfibrillar-associated protein 2 (MFAP2), a component of the extracellular matrix, is
important in controlling growth factor signal transduction. Recent studies have shown that …

Ovarian cancer is one of the most common gynecological tumors that seriously endanger
the health and quality of life of women. Microfibril‐associated protein 2 (MFAP2) has been …

MFAP2 has been reported to play an oncogenic role in several types of human cancers.
However, the expression profile of MFAP2 in various cancers and its impact on prognosis …

Abnormal expression of microfibrillar‑associated protein 2 (MFAP2), a key regulator of
cellular differentiation, affects the occurrence and progression of tumors. However, the …

Endometrial cancer, which is the most common gynaecological cancer in women after
breast, colorectal and lung cancer, can be diagnosed at an early stage. The first aim of this …

Background The causal relationship between familial hypercholesterolemia (FH) and
various vitamin deficiencies has not yet been elucidated. Therefore, this study investigated …