Management of epilepsy in pregnancy: a report from the International League Against Epilepsy Task Force on Women and Pregnancy

T Tomson, D Battino, R Bromley, S Kochen… - Epileptic …, 2019 - shs.cairn.info
Management of epilepsy in pregnancy: a report from the International League Against Epilepsy
Task Force on Women and Pregnancy | Cairn.info Cairn.info, Matières à réflexion Cairn.info …

Drugs in pregnancy: pharmacologic and physiologic changes that affect clinical care

EA Pinheiro, CS Stika - Seminars in perinatology, 2020 - Elsevier
Pharmacologic interventions play a major role in obstetrical care throughout pregnancy,
labor and delivery and the postpartum. Traditionally, obstetrical providers have utilized …

Antiseizure medication concentrations during pregnancy: results from the maternal outcomes and neurodevelopmental effects of antiepileptic drugs (MONEAD) study

PB Pennell, A Karanam, KJ Meador, E Gerard… - JAMA …, 2022 - jamanetwork.com
Importance During pregnancy in women with epilepsy, lower blood concentrations of
antiseizure medications can have adverse clinical consequences. Objective To characterize …

Antiepileptic drug exposure in infants of breastfeeding mothers with epilepsy

AK Birnbaum, KJ Meador, A Karanam, C Brown… - JAMA …, 2020 - jamanetwork.com
Importance There is limited information on infant drug exposure via breastfeeding by
mothers who are receiving antiepileptic drug therapy. Objective To provide direct, objective …

Use of phenytoin, phenobarbital carbamazepine, levetiracetam lamotrigine and valproate in pregnancy and breastfeeding: risk of major malformations, dose …

YC Kaplan, O Demir - Current neuropharmacology, 2021 - benthamdirect.com
It is challenging to balance the fetal risks associated with the use of antiepileptic drugs
(AEDs) against maternal and fetal risks of seizure worsening, and therefore it is very …

Management of anti-seizure medications during pregnancy: advancements in the past decade

C Avachat, JM Barry, X Lyu, CM Sherwin, AK Birnbaum - Pharmaceutics, 2022 - mdpi.com
Management of seizures often involves continuous medication use throughout a patient's
life, including when a patient is pregnant. The physiological changes during pregnancy can …

Pharmacokinetic data in pregnancy: A review of available literature data and important considerations in collecting clinical data

P Coppola, E Kerwash, J Nooney, A Omran… - Frontiers in …, 2022 - frontiersin.org
Pregnancy-related physiological changes can alter the absorption, distribution, metabolism
and excretion of medicines which may affect the safety and efficacy of the medicines …

Sex and gender differences in epilepsy

L Hophing, P Kyriakopoulos, E Bui - International Review of Neurobiology, 2022 - Elsevier
Sex and gender differences in epilepsy are important influencing factors in epilepsy care. In
epilepsy, the hormonal differences between the sexes are important as they impact specific …

Estrogen profile-and pharmacogenetics-based lamotrigine dosing regimen optimization: recommendations for pregnant women with epilepsy

ML Wang, YY Tao, XY Sun, Y Guo, ZY Wang… - Pharmacological …, 2021 - Elsevier
During pregnancy, various physiological changes occur that can alter the pharmacokinetics
of antiepileptic drugs, such as lamotrigine (LTG). Anticipating the change in LTG dose …

Psychotropic drug use in perinatal women with bipolar disorder

CT Clark - Seminars in Perinatology, 2020 - Elsevier
Optimal dose management of psychotropic drugs during the perinatal period reduces the
risk for recurrence of mood episodes in women with Bipolar Disorder. Physiological changes …