Chitosan-based nanoparticles as drug delivery systems: a review on two decades of research

S Naskar, K Kuotsu, S Sharma - Journal of drug targeting, 2019 - Taylor & Francis
Chitosan (CS) is one of the most functional natural biopolymer widely used in the
pharmaceutical field due to its biocompatibility and biodegradability. These privileges lead …

Engineered nanomaterials for infection control and healing acute and chronic wounds

M Parani, G Lokhande, A Singh… - ACS Applied Materials & …, 2016 - ACS Publications
Nanoengineered biomaterials have dramatically expanded the range of tools used for
infection control and to accelerate wound healing. This review thoroughly describes the …

Chitosan-based drug nanocarriers: where do we stand?

M Garcia-Fuentes, MJ Alonso - Journal of Controlled Release, 2012 - Elsevier
Chitosan-based nanocarriers have become one of the most intensively studied
transmucosal nanometric drug delivery platforms. This is due to a number of factors …

Opening of epithelial tight junctions and enhancement of paracellular permeation by chitosan: microscopic, ultrastructural, and computed-tomographic observations

K Sonaje, EY Chuang, KJ Lin, TC Yen… - Molecular …, 2012 - ACS Publications
This study investigates the effects of chitosan (CS) on the opening of epithelial tight junctions
(TJs) and paracellular transport at microscopic, ultrastructural, and computed-tomographic …

Chitosan nanoparticles: shedding light on immunotoxicity and hemocompatibility

S Jesus, AP Marques, A Duarte, E Soares… - … in bioengineering and …, 2020 - frontiersin.org
Nanoparticles (NPs) assumed an important role in the area of drug delivery. Despite the
number of studies including NPs are growing over the last years, their side effects on the …

Chitosan nanoparticles: a contribution to nanomedicine

H Peniche, C Peniche - Polymer International, 2011 - Wiley Online Library
Chitosan is a cationic polysaccharide that finds diverse applications in medicine and
pharmacy because of its excellent biological qualities: it is biocompatible, biodegradable …

Recent advancements in nanotechnological strategies in selection, design and delivery of biomolecules for skin regeneration

PS Korrapati, K Karthikeyan, A Satish… - Materials Science and …, 2016 - Elsevier
Skin is a very complex organ and hence designing a bioengineered skin model replicating
the essential physiological characteristics for replacing the diseased or damaged parts has …

Targeting experimental orthotopic glioblastoma with chitosan-based superparamagnetic iron oxide nanoparticles (CS-DX-SPIONs)

M Shevtsov, B Nikolaev, Y Marchenko… - International Journal …, 2018 - Taylor & Francis
Background Glioblastoma is the most devastating primary brain tumor of the central nervous
system in adults. Magnetic nanocarriers may help not only for a targeted delivery of …

Covalently stabilized trimethyl chitosan-hyaluronic acid nanoparticles for nasal and intradermal vaccination

RJ Verheul, B Slütter, SM Bal, JA Bouwstra… - Journal of controlled …, 2011 - Elsevier
The physical stability of polyelectrolyte nanocomplexes composed of trimethyl chitosan
(TMC) and hyaluronic acid (HA) is limited in physiological conditions. This may minimize the …

Poly-(ethylene glycol) modified gelatin nanoparticles for sustained delivery of the anti-inflammatory drug Ibuprofen-Sodium: An in vitro and in vivo analysis

D Narayanan, MG Geena, H Lakshmi… - … , Biology and Medicine, 2013 - Elsevier
The limited bioavailability and rapid clearance of the anti-inflammatory drug Ibuprofen
Sodium (IbS) necessitates repeated drug administration. To address this, injectable IbS …