The insulin-like growth factors and feto-placental growth
AL Fowden - Placenta, 2003 - Elsevier
The insulin-like growth factors, IGF-I and IGF-II, have an important role in fetoplacental
growth throughout gestation. They have metabolic, mitogenic and differentiative actions in a …
growth throughout gestation. They have metabolic, mitogenic and differentiative actions in a …
Placental efficiency and adaptation: endocrine regulation
Size at birth is critical in determining life expectancy and is dependent primarily on the
placental supply of nutrients. However, the fetus is not just a passive recipient of nutrients …
placental supply of nutrients. However, the fetus is not just a passive recipient of nutrients …
Placental-specific IGF-II is a major modulator of placental and fetal growth
Imprinted genes in mammals are expressed from only one of the parental chromosomes,
and are crucial for placental development and fetal growth,,,. The insulin-like growth factor II …
and are crucial for placental development and fetal growth,,,. The insulin-like growth factor II …
Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero
The embryo instructs the allocation of cell states to spatially regulate functions. In the
blastocyst, patterning of trophoblast (TR) cells ensures successful implantation and …
blastocyst, patterning of trophoblast (TR) cells ensures successful implantation and …
Placental phenotype and the insulin‐like growth factors: resource allocation to fetal growth
AN Sferruzzi‐Perri, I Sandovici… - The Journal of …, 2017 - Wiley Online Library
The placenta is the main determinant of fetal growth and development in utero. It supplies all
the nutrients and oxygen required for fetal growth and secretes hormones that facilitate …
the nutrients and oxygen required for fetal growth and secretes hormones that facilitate …
Regulation of supply and demand for maternal nutrients in mammals by imprinted genes
The placenta has evolved in eutherian mammals primarily to provide nutrients for the
developing fetus. The genetic control of the regulation of supply and demand for maternal …
developing fetus. The genetic control of the regulation of supply and demand for maternal …
Evidence for placental abnormality as the major cause of mortality in first-trimester somatic cell cloned bovine fetuses
The production of cloned animals is, at present, an inefficient process. This study focused on
the fetal losses that occur between Days 30–90 of gestation. Fetal and placental …
the fetal losses that occur between Days 30–90 of gestation. Fetal and placental …
Placental adaptations to the maternal–fetal environment: implications for fetal growth and developmental programming
I Sandovici, K Hoelle, E Angiolini… - Reproductive biomedicine …, 2012 - Elsevier
The placenta is a transient organ found in eutherian mammals that evolved primarily to
provide nutrients for the developing fetus. The placenta exchanges a wide array of nutrients …
provide nutrients for the developing fetus. The placenta exchanges a wide array of nutrients …
Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems
M Constância, E Angiolini, I Sandovici… - Proceedings of the …, 2005 - National Acad Sciences
The mammalian fetus is unique in its dependence during gestation on the supply of
maternal nutrients through the placenta. Maternal supply and fetal demand for nutrients …
maternal nutrients through the placenta. Maternal supply and fetal demand for nutrients …
Imprinted genes, placental development and fetal growth
In mammals, imprinted genes have an important role in feto-placental development. They
affect the growth, morphology and nutrient transfer capacity of the placenta and, thereby …
affect the growth, morphology and nutrient transfer capacity of the placenta and, thereby …