The Bacillus cereus group includes several Bacillus species with closely related phylogeny.
The most well-studied members of the group, B. anthracis, B. cereus, and B. thuringiensis …

Pore-forming toxins (PFTs) are virulence factors produced by many pathogenic bacteria and
have long fascinated structural biologists, microbiologists and immunologists. Interestingly …

Virulence is described as an ability of an organism to infect the host and cause a disease.
Virulence factors are the molecules that assist the bacterium colonize the host at the cellular …

Abstract Cholesterol 25-hydroxylase (CH25H) is an interferon-stimulated gene that converts
cholesterol to the oxysterol 25-hydroxycholesterol (25HC). Circulating 25HC modulates …

Cells employ regulated transport mechanisms to ensure that their plasma membranes (PMs)
are optimally supplied with cholesterol derived from uptake of low-density lipoproteins (LDL) …

The Bacillus cereus sensu lato group contains diverse Gram-positive spore-forming bacteria
that can cause gastrointestinal diseases and severe eye infections in humans. They have …

Membrane attack complex/perforin/cholesterol-dependent cytolysin (MACPF/CDC) proteins
constitute a major superfamily of pore-forming proteins that act as bacterial virulence factors …

The recognition and binding of cholesterol is an important feature of many eukaryotic, viral,
and prokaryotic proteins, but the molecular details of such interactions are understood only …

The cholesterol-dependent cytolysins (CDCs) are a large family of pore-forming toxins that
are produced, secreted and contribute to the pathogenesis of many species of Gram-positive …

Listeriolysin O (LLO) is an essential virulence factor of Listeria monocytogenes that causes
listeriosis. Listeria monocytogenes owes its ability to live within cells to the pH-and …