Background: Hepatic platelet accumulation contributes to acetaminophen (APAP)-induced
liver injury (AILI). However, little is known about the molecular pathways involved in platelet …

Introduction: Before being implemented in daily clinical routine, new production strategies
for platelet concentrates (PCs) must be validated for their efficacy. Besides in vitro testing …

Acute inflammation begins with leukocyte P-selectin glycoprotein ligand-1 (PSGL-1) binding
to P-selectin on inflamed endothelium and platelets. In pathologic conditions, this process …

G protein–coupled receptors are critical mediators of platelet activation whose signaling can
be modulated by members of the regulator of G protein signaling (RGS) family. The 2 most …

Inflammation and thrombosis are complex processes that occur primarily in the
microcirculation. Although standard histology may provide insight into the end pathway for …

In addition to their roles in hemostasis and thrombosis, platelets are now recognized as
making important contributions to a wide variety of inflammatory responses. This function …

Die Hämostase und die Bildung von Thromben sind von großer Bedeutung für den
Organismus um Blutverluste zu vermeiden. Eine überschießende Thrombusbildung hat …

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Home About Overview Sharing Data ORCID Help History (1) RUMBAUT, ROLANDO See All …

The knowledge gained through imaging platelets has formed the backbone of our
understanding of their biology in health and disease. Early investigators relied on …

G protein-coupled receptors (GPCRs) are critical mediators of platelet activation whose
signaling is limited in part by members of the regulator of G protein signaling (RGS) family …