Measurement of two groups of autoantibodies, rheumatoid factor (RF) and anti-citrullinated
protein/peptide antibodies (ACPA) have gained increasing significance in the diagnosis and …

Rheumatoid arthritis is an autoimmune syndrome presenting with chronic inflammation of
the joints. Patients with the same diagnosis can present with different phenotypes. In some …

Ideal biomarkers used for disease diagnosis should display deviating levels in affected
individuals only and be robust to factors unrelated to the disease. Here we show the impact …

Rheumatoid arthritis (RA) is a highly heterogeneous syndrome in terms of clinical
presentation, progression, and response to therapy. In such a complicated context, the …

Rheumatoid arthritis (RA) is an autoimmune disorder characterized by inflammation and
bone erosion. The exact mechanism of RA is still unknown, but various immune cytokines …

Autoimmune diseases (AIDs) share similar serological, clinical, and radiological findings,
but, behind these common features, there are different pathogenic mechanisms, immune …

Objectives. To review studies that address prediction of response to biologic treatment in RA
and to explore the clinical utility of the studied (bio) markers. Methods. A search for relevant …

Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by autoimmunity
that triggers joint inflammation and tissue destruction. Traditional concepts of RA …

Therapeutic blockage of cytokine signalling in autoimmune diseases has improved our
understanding of the role of these cytokines in triggering, shaping and perpetuating …

Objective Acute respiratory distress syndrome (ARDS) related to SARS-CoV-2 is likely due
to a cytokine storm characterised by a major release of pro-inflammatory cytokines, including …