Tissues like bone and cartilage are remodeled dynamically for their functional requirements
by signaling pathways. The signals are controlled by the cells and extracellular matrix and …

Adipose stem cells (ASCs) are an attractive and abundant stem cell source with therapeutic
applicability in diverse fields for the repair and regeneration of acute and chronically …

Abstract Treatment of delayed union, malunion, and nonunion is a challenge to the
orthopaedic surgeons in veterinary and human fields. Apart from restoration of alignment …

Articular cartilage repair and regeneration continue to be largely intractable because of the
poor regenerative properties of this tissue. The field of articular cartilage tissue engineering …

Background The management of articular cartilage defects presents many clinical
challenges due to its avascular, aneural and alymphatic nature. Bone marrow stimulation …

Osteoarthritis is a degenerative joint disease characterized by pain and disability. It involves
all ages and 70% of people aged> 65 have some degree of osteoarthritis. Natural cartilage …

Mesenchymal stromal cells (MSCs) can be isolated from various tissues such as bone
marrow aspirates, fat or umbilical cord blood. These cells have the ability to proliferate in …

PURPOSE: The purpose of this study was to compare histologic and magnetic resonance
imaging (MRI) evaluation of articular cartilage regeneration in patients with chondral lesions …

Purpose The aim of this systematic review is to examine the available clinical evidence in
the literature to support mesenchymal stem cell (MSC) treatment strategies in orthopaedics …

Articular cartilage (AC) lesions are fairly common but remain an obstacle for clinicians and
researchers due to their poor self-healing capacity. Recently, a promising therapy based on …