Clear cell renal cell carcinoma (ccRCC) is the most frequent histological kidney cancer
subtype. Over the last decade, significant progress has been made in identifying the genetic …

Cancer is a disorder of cell growth and proliferation, characterized by different metabolic
pathways within normal cells. The Warburg effect is a major metabolic process in cancer …

Chemotherapy is currently the main treatment for unresectable or advanced postoperative
gastric cancers. However, its efficacy is negatively affected by the occurrence of …

Genomic instability (GIN) is pivotal in regulating tumor drug resistance, which blocked the
treatment of triple negative breast cancer (TNBC). Although recent studies implied that non …

Background Breast cancer is a highly heterogeneous disease, this poses challenges for
classification and management. Long non-coding RNAs play acrucial role in the breast …

Clear cell renal cell carcinoma (ccRCC) is the most common malignant tumor of the kidney.
New and reliable biomarkers are in urgent need for ccRCC diagnosis and prognosis. The …

Cell death is a necessary event in life and is crucial for the regulation of organismal
development, homeostasis, aging and pathological conditions. There are different modes of …

Colorectal cancer (CRC) is one of the main fatal cancers. Cell signaling such as Janus
kinase/signal transducer and activator of transcription (JAK/STAT) signaling substantially …

With the development of sequencing technology, a large number of long non-coding RNAs
(lncRNAs) have been identified in addition to coding genes. LncRNAs, originally considered …

The human genome encodes thousands of natural antisense long noncoding RNAs
(lncRNAs); they play the essential role in regulation of gene expression at multiple levels …