Intestinal epithelial barrier function and tight junction proteins with heat and exercise

K Dokladny, MN Zuhl… - Journal of applied …, 2016 - journals.physiology.org
A single layer of enterocytes and tight junctions (intercellular multiprotein complexes) form
the intestinal epithelial barrier that controls transport of molecules through transcellular and …

Ischemia—reperfusion injury of the intestine and protective strategies against injury

IH Mallick, W Yang, MC Winslet… - Digestive diseases and …, 2004 - Springer
Ischemia—Reperfusion injury of the intestine is a significant problem in abdominal aortic
aneurysm surgery, small bowel transplantation, cardiopulmonary bypass, strangulated …

Depression, stress and immunological activation: the role of cytokines in depressive disorders

TJ Connor, BE Leonard - Life sciences, 1998 - Elsevier
Traditionally, both stress and depression have been associated with impaired immune
function and increased susceptibility to infectious and neoplastic disease. However over the …

Heat‐shock proteins

Z Li, P Srivastava - Current protocols in immunology, 2003 - Wiley Online Library
Abstract Heat‐shock proteins (HSPs), or stress proteins, are highly conserved and present in
all organisms and in all cells of all organisms. Selected HSPs, also known as chaperones …

Heat shock proteins and heat adaptation of the whole organism

PL Moseley - Journal of applied physiology, 1997 - journals.physiology.org
Moseley, Pope L. Heat shock proteins and heat adaptation of the whole organism. J. Appl.
Physiol. 83 (5): 1413–1417, 1997.—Adaptation to heat may occur through acclimatization or …

Heat shock proteins and cardiovascular pathophysiology

LHEH Snoeckx, RN Cornelussen… - Physiological …, 2001 - journals.physiology.org
In the eukaryotic cell an intrinsic mechanism is present providing the ability to defend itself
against external stressors from various sources. This defense mechanism probably evolved …

Association of body temperature and antipyretic treatments with mortality of critically ill patients with and without sepsis: multi-centered prospective observational study

Fever and Antipyretic in Critically ill patients Evaluation … - Critical care, 2012 - Springer
Introduction Fever is frequently observed in critically ill patients. An independent association
of fever with increased mortality has been observed in non-neurological critically ill patients …

Physiologically relevant increase in temperature causes an increase in intestinal epithelial tight junction permeability

K Dokladny, PL Moseley, TY Ma - American Journal of …, 2006 - journals.physiology.org
The effects of physiologically relevant increase in temperature (37–41° C) on intestinal
epithelial tight junction (TJ) barrier have not been previously studied. Additionally, the role of …

Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy

K Dokladny, MN Zuhl, M Mandell… - Journal of Biological …, 2013 - ASBMB
The eukaryotic cell depends on multitiered homeostatic systems ensuring maintenance of
proteostasis, organellar integrity, function and turnover, and overall cellular viability. At the …

Sequestration of TRAF2 into stress granules interrupts tumor necrosis factor signaling under stress conditions

WJ Kim, SH Back, V Kim, I Ryu… - Molecular and cellular …, 2005 - Am Soc Microbiol
The cellular stress response (SR) is a phylogenetically conserved protection mechanism
that involves inhibition of protein synthesis through recruitment of translation factors such as …