The world of small noncoding RNAs (sncRNAs) is ever-expanding, from small interfering RNA, microRNA and Piwi-interacting RNA to the recently emerging non-canonical sncRNAs …
Newly growing evidence highlights the essential role that epitranscriptomic marks play in the development of many cancers; however, little is known about the role and implications of …
K Li, Y Lin, Y Luo, X Xiong, L Wang, K Durante, J Li… - Molecular cancer, 2022 - Springer
Background The tRNA-derived small RNAs (tsRNAs) are produced in a nuclease- dependent manner in responses to variety of stresses that are common in cancers. We focus …
Although high-throughput RNA sequencing (RNA-seq) has greatly advanced small non- coding RNA (sncRNA) discovery, the currently widely used complementary DNA library …
As one of the most abundant and conserved RNA species, transfer RNAs (tRNAs) are well known for their role in reading the codons on messenger RNAs and translating them into …
Transfer-RNA-derived small RNAs (tsRNAs; also called tRNA-derived fragments) are an abundant class of small non-coding RNAs whose biological roles are not well understood …
JA Saba, K Liakath-Ali, R Green, FM Watt - Nature reviews Molecular …, 2021 - nature.com
Stem cells are characterized by their ability to self-renew and differentiate into many different cell types. Research has focused primarily on how these processes are regulated at a …
AM Pinzaru, SF Tavazoie - Nature Reviews Cancer, 2023 - nature.com
Transfer RNAs (tRNAs) have been historically viewed as non-dynamic adaptors that decode the genetic code into proteins. Recent work has uncovered dynamic regulatory roles for …