Cardiac surgery is associated with perioperative blood loss and a high risk of allogeneic
blood transfusion. Patient blood management (PBM) in cardiac surgery contributes to the …

The invention of CPB revolutionized cardiac surgery. This vital tool has been continuously
refined over the years. Today, achieving excellent results depends on a team approach and …

Document Reviewers: Moritz WV Wyler von Ballmoos (USA), Mate Petricevic (Croatia), Arie
Pieter Kappetein (Netherlands), Miguel Sousa-Uva (Portugal), Georg Trummer (Germany) …

Neutralisation of systemic anticoagulation with heparin in cardiac surgery with
cardiopulmonary bypass requires protamine administration. If adequately dosed, protamine …

Cardiopulmonary bypass (CPB) is a unique clinical scenario that results in widespread
activation of the hemostatic system. However, surgery also results in normal increases in …

716-Kunst et al. according to the study design and the internal hierarchy based on the study
quality were used to formulate levels and grades of recommendations. In the absence of …

Background: We assessed the effects of protamine overdosing on thrombelastometry,
bleeding, and transfusions in patients after cardiopulmonary bypass (CPB). Methods: In …

Disclaimer 2019: The EACTS/EACTA/EBCP Guidelines represent the views of the EACTS,
the EACTA and EBCP and were produced after careful consideration of the scientific and …

Objectives Point-of-care (POC) testing is generally less precise and has higher reagent
costs per test than laboratory-based assays. However, POC hemostasis testing can offer …

Without anticoagulation, cardiopulmonary bypass would not have developed over the last
nearly 60 years into one of the most influential innovations in medicine; without the ability to …