Sex differences in autism spectrum disorder: a review
Abstract Purpose of Review Neurodevelopmental disorders disproportionately affect males.
The mechanisms underlying male vulnerability or female protection are not known and …
The mechanisms underlying male vulnerability or female protection are not known and …
16p11. 2 copy number variations and neurodevelopmental disorders
Copy number variations (CNVs) of the human 16p11. 2 genetic locus are associated with a
range of neurodevelopmental disorders, including autism spectrum disorder, intellectual …
range of neurodevelopmental disorders, including autism spectrum disorder, intellectual …
Vascular contributions to 16p11. 2 deletion autism syndrome modeled in mice
While the neuronal underpinnings of autism spectrum disorder (ASD) are being unraveled,
vascular contributions to ASD remain elusive. Here, we investigated postnatal …
vascular contributions to ASD remain elusive. Here, we investigated postnatal …
Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism
SC Dhamne, JL Silverman, CE Super, SHT Lammers… - Molecular autism, 2017 - Springer
Background Autism spectrum disorder (ASD) is a clinically and biologically heterogeneous
condition characterized by social, repetitive, and sensory behavioral abnormalities. No …
condition characterized by social, repetitive, and sensory behavioral abnormalities. No …
Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function
I Lundgaard, W Wang, A Eberhardt, HS Vinitsky… - Scientific reports, 2018 - nature.com
Prolonged intake of excessive amounts of ethanol is known to have adverse effects on the
central nervous system (CNS). Here we investigated the effects of acute and chronic ethanol …
central nervous system (CNS). Here we investigated the effects of acute and chronic ethanol …
Cerebellum-specific deletion of the GABAA receptor δ subunit leads to sex-specific disruption of behavior
Granule cells (GCs) of the cerebellar input layer express high-affinity δ GABA A subunit-
containing GABA A receptors (δGABA A Rs) that respond to ambient GABA levels and …
containing GABA A receptors (δGABA A Rs) that respond to ambient GABA levels and …
Sleep, brain development, and autism spectrum disorders: Insights from animal models
Sleep is an evolutionarily conserved and powerful drive, although its complete functions are
still unknown. One possible function of sleep is that it promotes brain development. The …
still unknown. One possible function of sleep is that it promotes brain development. The …
Hemiplegic Migraine Associated With PRRT2 Variations: A Clinical and Genetic Study
F Riant, C Roos, A Roubertie, C Barbance, J Hadjadj… - Neurology, 2022 - AAN Enterprises
Background and Objective PRRT2 variants have been reported in a few cases of patients
with hemiplegic migraine. To clarify the role of PRRT2 in familial hemiplegic migraine, we …
with hemiplegic migraine. To clarify the role of PRRT2 in familial hemiplegic migraine, we …
Shank3 modulates sleep and expression of circadian transcription factors
Autism Spectrum Disorder (ASD) is the most prevalent neurodevelopmental disorder in the
United States and often co-presents with sleep problems. Sleep problems in ASD predict the …
United States and often co-presents with sleep problems. Sleep problems in ASD predict the …
Targeting NR1D1 in organ injury: challenges and prospects
ZY Zhang-Sun, XZ Xu, G Escames, WR Lei… - Military Medical …, 2023 - Springer
Nuclear receptor subfamily 1, group D, member 1 (NR1D1, also known as REV-ERBα)
belongs to the nuclear receptor (NR) family, and is a heme-binding component of the …
belongs to the nuclear receptor (NR) family, and is a heme-binding component of the …