Antibiotics and mental health: The good, the bad and the ugly

K Dinan, T Dinan - Journal of Internal Medicine, 2022 - Wiley Online Library
Antibiotics are recognised as, on occasion, producing psychiatric side effects, most notably
depression and anxiety. Apart from antimicrobial activity, antibiotics have multiple off‐target …

Clinical considerations for the diagnosis of idiopathic hypersomnia

Y Dauvilliers, RK Bogan, I Arnulf, TE Scammell… - Sleep Medicine …, 2022 - Elsevier
Idiopathic hypersomnia is a sleep disorder of neurologic origin characterized by excessive
daytime sleepiness, with sleep inertia, long, unrefreshing naps, and prolonged nighttime …

Update on the treatment of idiopathic hypersomnia: progress, challenges, and expert opinion

I Arnulf, R Thomas, A Roy, Y Dauvilliers - Sleep Medicine Reviews, 2023 - Elsevier
Idiopathic hypersomnia is a central hypersomnolence disorder of unknown origin
characterized by excessive daytime sleepiness despite normal or long sleep time, and …

Sleepiness in neurological disorders

AL Dubessy, I Arnulf - Revue Neurologique, 2023 - Elsevier
Sleepiness is a frequent and underrecognized symptom in neurological disorders, that
impacts functional outcomes and quality of life. Multiple and potentially additive factors might …

Comparative polysomnography parameters between narcolepsy type 1/type 2 and idiopathic hypersomnia: a systematic review and meta-analysis

Y Zhang, R Ren, L Yang, H Zhang, Y Shi… - Sleep Medicine …, 2022 - Elsevier
A meta-analysis exploring polysomnography (PSG) differences between narcolepsy type 1
(NT1)/type 2 (NT2) and idiopathic hypersomnia (IH), particularly one that stratifies the …

Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: a phase 3, placebo-controlled, double-blind, randomised withdrawal study

Y Dauvilliers, I Arnulf, N Foldvary-Schaefer… - The Lancet …, 2022 - thelancet.com
Background Idiopathic hypersomnia is a central hypersomnolence disorder mainly
characterised by excessive daytime sleepiness, with prolonged night-time sleep and …

Sleep inertia measurement with the psychomotor vigilance task in idiopathic hypersomnia

E Evangelista, AL Rassu, R Lopez, N Biagioli… - Sleep, 2022 - academic.oup.com
Abstract Study Objectives Sleep inertia is a frequent and disabling symptom in idiopathic
hypersomnia (IH), but poorly defined and without objective measures. The study objective …

Genetics and epigenetics of rare hypersomnia

MP Mogavero, LM DelRosso, O Bruni, M Salemi… - Trends in Genetics, 2023 - cell.com
Herein we focus on connections between genetics and some central disorders of
hypersomnolence–narcolepsy types 1 and 2 (NT1, NT2), idiopathic hypersomnia (IH), and …

Stability of nocturnal wake and sleep stages defines central nervous system disorders of hypersomnolence

KP Maski, A Colclasure, E Little, E Steinhart… - Sleep, 2021 - academic.oup.com
Abstract Study Objectives We determine if young people with narcolepsy type 1 (NT1),
narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH) have distinct nocturnal sleep …

The melanopsin-mediated pupil response is reduced in idiopathic hypersomnia with long sleep time

H Rach, U Kilic-Huck, E Reynaud, L Hugueny… - Scientific reports, 2022 - nature.com
Idiopathic hypersomnia (IH), characterized by an excessive day-time sleepiness, a
prolonged total sleep time on 24 h and/or a reduced sleep latency, affects 1 in 2000 …